Cytotoxicity Evaluation of Two Different Composites with/ without Fibers and One Nanohybrid Composite

In this study, cytotoxicity of two different composites with/ without fibers (Adoro/ Vectris and SculpturePlus/ FiberKor) and one nanohybrid composite (Artglass) were investigated and compared. Composites used in the study were prepared as cylindrical discs of 2 mm depth and 8 mm diameter according...

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Published inDental Materials Journal Vol. 25; no. 2; pp. 267 - 271
Main Authors TUNÇEL, Aykut, ÖZDEMIR, Ali Kemal, SÜMER, Zeynep, HÜRMÜZLÜ, Feridun, POLAT, Zübeyde
Format Journal Article
LanguageEnglish
Published Japan The Japanese Society for Dental Materials and Devices 01.06.2006
Subjects
Analysis of Variance
Animals
Composite Resins - chemistry
Composite Resins - toxicity
Cytotoxicity
Fiber-reinforced systems
Fibroblasts - drug effects
Glass
Immunodiffusion
L Cells (Cell Line)
Mice
Nanohybrid composite
Polymethyl Methacrylate - toxicity
Statistics, Nonparametric
Online AccessGet full text

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Abstract In this study, cytotoxicity of two different composites with/ without fibers (Adoro/ Vectris and SculpturePlus/ FiberKor) and one nanohybrid composite (Artglass) were investigated and compared. Composites used in the study were prepared as cylindrical discs of 2 mm depth and 8 mm diameter according to ISO 10993 recommendation. Adoro/ Vectris and SculpturePlus/ FiberKor groups were divided into composite, fiber, and composite+fiber groups. Agar diffusion method was employed, and cytotoxicity rankings were determined using lysis index scores. For statistical analysis, Kruskal-Wallis and Mann-Whitney U tests were used. Amongst the composites, Adoro was found to be less cytotoxic than Sculpture Plus and Artglass materials — which were of the same cytotoxicity ranking. Between the fiber and composite materials, the former were found to be more cytotoxic than the latter; in particular, Vectris was found to be more cytotoxic than FiberKor. It was observed that upon combining with the fibers, the cytotoxic effect of the composites increased. This cytotoxicity enhancement was manifested as an additional effect in Adoro/ Vectris group but as a synergistic effect in SculpturePlus/ FiberKor group.
AbstractList In this study, cytotoxicity of two different composites with/ without fibers (Adoro/ Vectris and SculpturePlus/ FiberKor) and one nanohybrid composite (Artglass) were investigated and compared. Composites used in the study were prepared as cylindrical discs of 2 mm depth and 8 mm diameter according to ISO 10993 recommendation. Adoro/ Vectris and SculpturePlus/ FiberKor groups were divided into composite, fiber, and composite+fiber groups. Agar diffusion method was employed, and cytotoxicity rankings were determined using lysis index scores. For statistical analysis, Kruskal-Wallis and Mann-Whitney U tests were used. Amongst the composites, Adoro was found to be less cytotoxic than Sculpture Plus and Artglass materials — which were of the same cytotoxicity ranking. Between the fiber and composite materials, the former were found to be more cytotoxic than the latter; in particular, Vectris was found to be more cytotoxic than FiberKor. It was observed that upon combining with the fibers, the cytotoxic effect of the composites increased. This cytotoxicity enhancement was manifested as an additional effect in Adoro/ Vectris group but as a synergistic effect in SculpturePlus/ FiberKor group.
Author POLAT, Zübeyde
TUNÇEL, Aykut
HÜRMÜZLÜ, Feridun
ÖZDEMIR, Ali Kemal
SÜMER, Zeynep
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  fullname: ÖZDEMIR, Ali Kemal
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SubjectTerms Analysis of Variance
Animals
Composite Resins - chemistry
Composite Resins - toxicity
Cytotoxicity
Fiber-reinforced systems
Fibroblasts - drug effects
Glass
Immunodiffusion
L Cells (Cell Line)
Mice
Nanohybrid composite
Polymethyl Methacrylate - toxicity
Statistics, Nonparametric
Title Cytotoxicity Evaluation of Two Different Composites with/ without Fibers and One Nanohybrid Composite
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https://www.ncbi.nlm.nih.gov/pubmed/16916228
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