Clinical Microwave Tomographic Imaging of the Calcaneus: A First-in-Human Case Study of Two Subjects

• Published in: IEEE transactions on biomedical engineering Vol. 59; no. 12; pp. 3304 - 3313
• Main Authors: Meaney, Paul M., Goodwin, Douglas, Golnabi, Amir H., Zhou, Tian, Pallone, Matthew, Geimer, Shireen D., Burke, Gregory, Paulsen, Keith D.
• Format: Journal Article
• Language: English
• Published: New York, NY IEEE 01.12.2012; Institute of Electrical and Electronics Engineers; The Institute of Electrical and Electronics Engineers, Inc. (IEEE)
• Subjects: Adult; Biological and medical sciences; Bone; bone density; Bone Density - physiology; Bones; Calcaneus - anatomy & histology; Calcaneus - diagnostic imaging; Calcaneus - pathology; Computed tomography; dielectric properties; Diseases of the osteoarticular system; Electric Conductivity; Electrical properties; Exact sciences and technology; Female; fracture risk; Fundamental areas of phenomenology (including applications); Humans; Image reconstruction; tomography; Imaging and optical processing; Imaging, Three-Dimensional - methods; Investigative techniques, diagnostic techniques (general aspects); Male; Medical sciences; Microwave imaging; Microwave measurements; Microwave theory and techniques; Microwaves; Optics; Osteoarticular system. Muscles; osteoporosis; Osteoporosis. Osteomalacia. Paget disease; Physics; Radiodiagnosis. Nmr imagery. Nmr spectrometry; Tomography - methods; Tomography, X-Ray Computed - methods; Ultrasonography; Human; Dielectric properties; Diseases of the osteoarticular system; Rupture; bone density; Fracture; Trauma; Calcaneum; fracture risk; Osteoarticular system; Case study; Osteoporosis; microwave imaging; Risk factor; Bone mineral density; Bone; Biomedical engineering

We have acquired 2-D and 3-D microwave tomographic images of the calcaneus bones of two patients to assess correlation of the microwave properties with X-ray density measures. The two volunteers were selected because each had one leg immobilized for at least six weeks during recovery from a lower le...