Gut microbiota and renin-angiotensin system: a complex interplay at local and systemic levels

• Published in: American journal of physiology: Gastrointestinal and liver physiology Vol. 321; no. 4; pp. G355 - G366
• Main Authors: Jaworska, Kinga, Koper, Mateusz, Ufnal, Marcin
• Format: Journal Article
• Language: English
• Published: Bethesda American Physiological Society 01.10.2021
• Series: Microbiome-Based Therapeutics and Their Physiological Effects
• Subjects: Aging; Angiotensin; Carcinogenesis; Cardiovascular system; Digestive system; Electrolyte balance; Endocrine system; Gastrointestinal diseases; Gastrointestinal tract; Gut microbiota; Homeostasis; Intestinal absorption; Intestinal microflora; Intestine; Microbiomes; Microbiota; Pharmacodynamics; Renin; Review

Gut microbiota is a potent biological modulator of many physiological and pathological states. The renin-angiotensin system (RAS), including the local gastrointestinal RAS (GI RAS), emerges as a potential mediator of microbiota-related effects. The RAS is involved in cardiovascular system homeostasi...