A small molecule exerts selective antiviral activity by targeting the human cytomegalovirus nuclear egress complex - Chen, Han; Lye, Ming F.; Gorgulla, Christoph; Ficarro, Scott B.; Cuny, Gregory D.; Scott, David A.; Wu, Fan; Rothlauf, Paul W.; Wang, Xiaoou; Fernandez, Rosio; Pesola, Jean M.; Draga, Sorin; et al. (PLoS pathogens, 2023)
Keywords: Ablation; Acrylamide; Amides; Antibodies; Antiviral activity; Antiviral agents; Antiviral drugs; Assaying; Chromatography; Complications and side effects; Cytomegalovirus; Cytomegalovirus infections; Cytotoxicity; Dosage and administration; Drug development; Drug resistance; Drug therapy; Egress; Energy transfer; Fluorescence; Health aspects; Hearing loss; Herpes viruses; Immunoprecipitation; Infants (Newborn); Infections; Insects; Kinases; Localization; Mass spectrometry; Patient outcomes; Physiological aspects; Prevention; Proteins; Replication; Risk factors; Spectrometry; Substitutes; Viral proteins; United States