Cellular Networks Involved in the Influenza Virus Life Cycle

• Published in: Cell host & microbe Vol. 7; no. 6; pp. 427 - 439
• Main Authors: Watanabe, Tokiko, Watanabe, Shinji, Kawaoka, Yoshihiro
• Format: Journal Article
• Language: English
• Published: United States 25.06.2010
• Subjects: Animals; Cell Line; Gene Knockdown Techniques - methods; Host-Pathogen Interactions; Humans; Orthomyxoviridae - growth & development; Orthomyxoviridae - pathogenicity; Orthomyxoviridae - physiology; Virus Replication

Influenza viruses cause epidemics and pandemics. Like all viruses, influenza viruses rely on the host cellular machinery to support their life cycle. Accordingly, identification of the host functions co-opted for viral replication is of interest to understand the mechanisms of the virus life cycle a...