Vitamin D and cardiovascular disease prevention

• Published in: Nature reviews cardiology Vol. 13; no. 7; pp. 404 - 417
• Main Authors: Pilz, Stefan, Verheyen, Nicolas, Grübler, Martin R., Tomaschitz, Andreas, März, Winfried
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.07.2016; Nature Publishing Group
• Subjects: 692/4019/592/75; 692/700/2814; 692/700/459; 692/700/459/1994; Alfacalcidol; Analysis; Calcifediol; Cardiac Imaging; Cardiac Surgery; Cardiology; Cardiovascular diseases; Health aspects; Innovations; Medicine & Public Health; Medicine, Preventive; Physiological aspects; Prevention; Preventive health services; review-article; Vitamin D

Key Points The vitamin D receptor (VDR) and enzymes for vitamin D metabolism are expressed throughout the cardiovascular system VDR and 1α-hydroxylase knockout mice have hypertension with myocardial hypertrophy and increased activity of the renin–angiotensin–aldosterone system The molecular effects...