Quantitative trait loci in Drosophila

• Published in: Nature reviews. Genetics Vol. 2; no. 1; pp. 11 - 20
• Main Author: Mackay, Trudy F. C
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.01.2001; Nature Publishing Group
• Subjects: Agriculture; Animal Genetics and Genomics; Animals; Biomedical and Life Sciences; Biomedicine; Cancer Research; Chromosome Mapping; Drosophila melanogaster - genetics; Female; Gene Function; Genes; Genetic engineering; Genomics; Genotype & phenotype; Human Genetics; Humans; Insects; Linkage Disequilibrium; Male; Mutagenesis; Mutation; Norms; Pharmaceutical industry; Quantitative genetics; Quantitative Trait, Heritable; review-article; North Carolina; United States > US

Key Points Quantitative trait phenotypes are continuously distributed in natural populations, due to segregation of alleles at multiple quantitative trait loci (QTL) and environmental sensitivity of QTL alleles. Determining the genetic and environmental bases of variation for quantitative traits is...