Development of recombinant West Nile virus expressing mCherry reporter protein

• Published in: Journal of virological methods Vol. 317; p. 114744
• Main Authors: Kobayashi, Shintaro, Fukuda, Yukine, Yoshii, Kentaro, Thammahakin, Passawat, Maezono, Keisuke, Eyer, Luděk, Růžek, Daniel, Kariwa, Hiroaki
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.07.2023
• Subjects: Animals; central nervous system; Culicidae; encephalitis; fluorescence; fluorescent proteins; Humans; Mice; Production of reporter virus; Recombinant Proteins - genetics; Reporter protein; therapeutics; West Nile Fever - veterinary; West Nile virus; West Nile virus - genetics; Reporter protein; West Nile virus; Production of reporter virus

West Nile virus (WNV) is transmitted to humans and animals by a mosquito and enters the central nervous system, leading to lethal encephalitis. Reporter viruses expressing fluorescent proteins enable detection of infected cells in vitro and in vivo, facilitating evaluation of the dynamics of viral i...