Preclinical and clinical advances in dual‐target chimeric antigen receptor therapy for hematological malignancies - Guo, Zhenling; Tu, Sanfang; Yu, Siyao; Wu, Liufang; Pan, Wanying; Chang, Ning; Zhou, Xuan; Song, Chaoyang; Li, Yuhua; He, Yanjie (Cancer science, 2021)
Keywords: Animals; antigen loss; Antigens; Antigens, Neoplasm - immunology; CD123 antigen; CD19 antigen; CD20 antigen; CD22 antigen; Cell therapy; chimeric antigen receptor; Chimeric antigen receptors; Cytokines; Cytotoxicity; dual‐target; Hematologic Neoplasms - immunology; Hematologic Neoplasms - therapy; hematological malignancies; Hematology; Humans; Immunotherapy; Immunotherapy - methods; Leukemia; Lymphocytes; Lymphocytes T; Lymphoma; Medical prognosis; Mutation; Peptides; Receptors, Antigen, T-Cell - immunology; Receptors, Chimeric Antigen - immunology; relapse; Response rates; Review; T-Lymphocytes - immunology; Tumors; hematological malignancies; dual-target; chimeric antigen receptor; antigen loss; relapse