Caspase-3/caspase-8, bax and bcl2 in pulps of human primary teeth with physiological root resorption

• Published in: International journal of paediatric dentistry Vol. 22; no. 1; pp. 52 - 59
• Main Authors: RODRIGUES, LUCIANA V., DEL PUERTO, HELEN L., BRANT, JULIANA M. C., LEITE, RÔMULO C., VASCONCELOS, ANILTON C.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.01.2012
• Subjects: Apoptosis; Apoptosis - physiology; Bax protein; Bcl-2 protein; bcl-2-Associated X Protein - genetics; bcl-2-Associated X Protein - metabolism; Caspase 3 - genetics; Caspase 3 - metabolism; Caspase 8 - genetics; Caspase 8 - metabolism; Caspase-3; Caspase-8; Dental pulp; Dental roots; Dentistry; Gene expression; Humans; Immunohistochemistry; Inflammation; Maxilla; Mitochondria; Molar, Third; Polymerase chain reaction; Proto-Oncogene Proteins c-bcl-2 - genetics; Proto-Oncogene Proteins c-bcl-2 - metabolism; RNA, Messenger - analysis; Root Resorption - metabolism; Teeth; Tooth, Deciduous - metabolism

International Journal of Paediatric Dentistry 2011; 22: 52–59 Objective.  Physiological root resorption is a programmed event that takes place in primary teeth leading to elimination of all root structures. The mechanism behind pulp elimination indicates apoptosis, but its pathway has not been well...