Phase‐contrast visualization of human tissues using superimposed wavefront imaging of diffraction‐enhanced x‐rays

• Published in: Medical physics (Lancaster) Vol. 51; no. 12; pp. 9179 - 9193
• Main Authors: Sunaguchi, Naoki, Yuasa, Tetsuya, Shimao, Daisuke, Huang, Zhuoran, Ichihara, Shu, Nishimura, Rieko, Iwakoshi, Akari, Kim, Jong‐Ki, Gupta, Rajiv, Ando, Masami
• Format: Journal Article
• Language: English
• Published: United States 01.12.2024
• Subjects: Algorithms; analyzer based refraction‐contrast CT; diffraction‐enhanced x‐rays; histopathology; Humans; Image Processing, Computer-Assisted - methods; Imaging, Three-Dimensional - methods; superimposed wavefront imaging; SWIDeX; synchrotron radiation; Tomography, X-Ray Computed - methods; X-Ray Diffraction; histopathology; SWIDeX; superimposed wavefront imaging; synchrotron radiation; analyzer based refraction‐contrast CT; diffraction‐enhanced x‐rays

Background Phase‐contrast computed tomography (CT) using high‐brilliance, synchrotron‐generated x‐rays enable three‐dimensional (3D) visualization of microanatomical structures within biological specimens, offering exceptionally high‐contrast images of soft tissues. Traditional methods for phase‐con...