Rice Protein Matrix Enhances Circulating Levels of Xanthohumol Following Acute Oral Intake of Spent Hops in Humans

• Published in: Molecular nutrition & food research Vol. 62; no. 6; pp. e1700692 - n/a
• Main Authors: O'Connor, Annalouise, Konda, Veera, Reed, Ralph L., Christensen, J. Mark, Stevens, Jan F., Contractor, Nikhat
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 01.03.2018
• Subjects: absorption; Administration, Oral; antioxidant activity; Antioxidants; Bioavailability; Consumption; Cross-Over Studies; Double-Blind Method; Female; flavonoids; Flavonoids - blood; Hops; human subjects; Humans; Humulus; Inflammation; Male; Metabolites; Oryza - chemistry; Plant Proteins, Dietary - administration & dosage; Plasma levels; polyphenols; Powder; Propiophenones - blood; Proteins; rice protein; Therapeutic applications; Xanthohumol; bioavailability; human subjects; xanthohumol

Scope Xanthohumol (XN), a prenylated flavonoid found in hops, exhibits anti‐inflammatory and antioxidant properties. However, poor bioavailability may limit therapeutic applications. As food components are known to modulate polyphenol absorption, the objective is to determine whether a protein matri...