Mechanistic Role of the Calcium-Dependent Protease Calpain in the Endothelial Dysfunction Induced by MPO (Myeloperoxidase)
MPO (myeloperoxidase) is a peroxidase enzyme secreted by activated leukocytes that plays a pathogenic role in cardiovascular disease, mainly by initiating endothelial dysfunction. The molecular mechanisms of the endothelial damaging action of MPO remain though largely elusive. Calpain is a calcium-d...
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Published in | Hypertension (Dallas, Tex. 1979) Vol. 71; no. 4; pp. 761 - 770 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
United States
American Heart Association, Inc
01.04.2018
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Subjects | |
Online Access | Get full text |
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