Expression and significance of microRNA‐126 and VCAM‐1 in placental tissues of women with early‐onset preeclampsia

• Published in: The journal of obstetrics and gynaecology research Vol. 47; no. 6; pp. 2042 - 2050
• Main Authors: Liu, Beibei, Liu, Ling, Cui, Shihong, Qi, Yue, Wang, Tiantian
• Format: Journal Article
• Language: English
• Published: Kyoto, Japan John Wiley & Sons Australia, Ltd 01.06.2021; Wiley Subscription Services, Inc
• Subjects: Cell adhesion molecules; Cell Movement; Endothelial cells; Female; Humans; Immunohistochemistry; microRNA; MicroRNAs; MicroRNAs - genetics; miRNA; Original; Placenta; Polymerase chain reaction; Pre-eclampsia; Pre-Eclampsia - genetics; Preeclampsia; Pregnancy; Statistical analysis; Transfection; Trophoblasts; Vascular Cell Adhesion Molecule-1 - genetics; VCAM‐1; microRNA; placenta; VCAM-1; preeclampsia

Objective To investigate the expression of microRNA‐126 (miR‐126) and vascular endothelial cell adhesion molecule‐1 (VCAM‐1) in the placental tissues of women with early‐onset preeclampsia (EOPE) and their effects on trophoblast invasion. Materials and Methods The placental tissues of 30 pregnant wo...