Screening a hybridoma producing a specific monoclonal antibody to HLA-A24+Bw4 antigen by cytotoxicity inhibition assay

A hybridoma secreting a monoclonal antibody (Tsa-1, IgG3) reacting specifically to HLA-A24+Bw4 was screened by cytotoxicity inhibition assay and micrototoxicity test. The R value of the antibody was 0.843.

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Bibliographic Details
Published inTissue antigens Vol. 29; no. 2; p. 120
Main Authors Hiroishi, S, Kaneko, T, Arita, J
Format Journal Article
LanguageEnglish
Published England 01.02.1987
Subjects
Antibodies, Monoclonal - immunology
beta 2-Microglobulin - immunology
Cytotoxicity, Immunologic
HLA Antigens - immunology
HLA-A Antigens
HLA-A24 Antigen
HLA-B Antigens
Humans
Hybridomas - immunology
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Summary:A hybridoma secreting a monoclonal antibody (Tsa-1, IgG3) reacting specifically to HLA-A24+Bw4 was screened by cytotoxicity inhibition assay and micrototoxicity test. The R value of the antibody was 0.843.
ISSN:0001-2815
1399-0039
DOI:10.1111/j.1399-0039.1987.tb01561.x