The integration of GC–MS and LC–MS to assay the metabolomics profiling in Panax ginseng and Panax quinquefolius reveals a tissue- and species-specific connectivity of primary metabolites and ginsenosides accumulation

• Published in: Journal of pharmaceutical and biomedical analysis Vol. 135; pp. 176 - 185
• Main Authors: Liu, Jia, Liu, Yang, Wang, Yu, Abozeid, Ann, Zu, Yuan-Gang, Tang, Zhong-Hua
• Format: Journal Article
• Language: English
• Published: England Elsevier B.V 20.02.2017
• Subjects: Carbon and nitrogen metabolism; Chromatography, Liquid - methods; Gas Chromatography-Mass Spectrometry - methods; Ginsenosides; Ginsenosides - analysis; Ginsenosides - metabolism; Metabolomics - methods; P. ginseng and P. quinquefolius; Panax - chemistry; Panax - metabolism; Plant Leaves - chemistry; Plant Leaves - metabolism; Plant Roots - chemistry; Plant Roots - metabolism; Saponins - analysis; Saponins - metabolism; Species Specificity; Tissue Distribution - physiology; Tissue specific; Carbon and nitrogen metabolism; Tissue specific; P. ginseng and P. quinquefolius; Ginsenosides

[Display omitted] •Tissue-specific profiling of primary and secondary metabolites in two different species of ginseng by using GC- and LC-MS.•Revealed a complex consecutive coordination of primary and secondary metabolism and corresponding pathways.•149 primary metabolites and 10 ginsenosides were i...