Thrombospondin: Synthesis and Secretion by Cells in Culture

• Published in: The Journal of cell biology Vol. 95; no. 1; pp. 351 - 354
• Main Authors: Raugi, Gregory J., Mumby, Susanne M., Abbott-Brown, Debbie, Bornstein, Paul
• Format: Journal Article
• Language: English
• Published: United States Rockefeller University Press 01.10.1982; The Rockefeller University Press
• Subjects: Animals; Antiserum; Aorta - metabolism; Cattle; Cell culture techniques; Cultured cells; Endothelial cells; Endothelium - metabolism; Fibroblasts; Fluorescence; Fluorescent Antibody Technique; Glycoproteins - biosynthesis; Glycoproteins - immunology; Glycoproteins - metabolism; Molecular Weight; Platelets; Rapid Communications; Smooth muscle myocytes; Thrombospondins; Ungulates

Thrombospondin, a high molecular weight glycoprotein secreted by platelets in response to activation by thrombin, has been identified by immunofluorescence in bovine aortic endothelial cells, human foreskin fibroblasts, and human aortic smooth muscle cells. Immunofluorescence patterns were found to...