Novel cardiac nuclear magnetic resonance method for noninvasive assessment of myocardial fibrosis in hemodialysis patients

• Published in: Kidney international Vol. 90; no. 4; pp. 835 - 844
• Main Authors: Graham-Brown, Matthew P.M., March, Daniel S., Churchward, Darren R., Stensel, David J., Singh, Anvesha, Arnold, Ranjit, Burton, James O., McCann, Gerry P.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.10.2016
• Subjects: Adult; Aged; cardiorenal; Female; Fibrosis; Heart - diagnostic imaging; hemodialysis; Humans; Hypertrophy, Left Ventricular - diagnostic imaging; Kidney Failure, Chronic - complications; Kidney Failure, Chronic - therapy; Magnetic Resonance Imaging - methods; Male; Middle Aged; MRI; Myocardium - pathology; native T1; Prospective Studies; Renal Dialysis - adverse effects; strain; Systole; native T1; strain; hemodialysis; cardiorenal; fibrosis; MRI
• ISSN: 0085-2538; 1523-1755
• DOI: 10.1016/j.kint.2016.07.014

Left ventricular hypertrophy and myocardial fibrosis frequently occur in patients with end-stage renal disease receiving hemodialysis therapy and are associated with poor prognosis. Native T1 mapping is a novel cardiac magnetic resonance imaging technique that measures native myocardial T1 relaxatio...