Cisplatin and radiation therapy in HIV-positive women with locally advanced cervical cancer in sub-Saharan Africa: A phase II study of the AIDS malignancy consortium

• Published in: Gynecologic oncology Vol. 153; no. 1; pp. 20 - 25
• Main Authors: Einstein, Mark H., Ndlovu, Ntokozo, Lee, Jeannette, Stier, Elizabeth A., Kotzen, Jeffrey, Garg, Madhur, Whitney, Kathleen, Lensing, Shelly Y., Tunmer, Mariza, Kadzatsa, Webster, Palefsky, Joel, Krown, Susan E.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.04.2019
• Subjects: Adult; Anti-Retroviral Agents - therapeutic use; Antineoplastic Agents - therapeutic use; Chemoradiotherapy; Cisplatin - therapeutic use; Female; HIV Infections - drug therapy; HIV Infections - pathology; Humans; Middle Aged; Neoplasm Staging; Prospective Studies; Radiation-Sensitizing Agents - therapeutic use; Uterine Cervical Neoplasms - drug therapy; Uterine Cervical Neoplasms - radiotherapy; Uterine Cervical Neoplasms - therapy; Uterine Cervical Neoplasms - virology

To determine the feasibility, safety, and tolerability of concomitant chemoradiotherapy administered at standard doses in HIV-infected women with locally-advanced cervical cancer (LACC) receiving antiretroviral therapy (ART). Eligible participants had HIV infection and untreated, histologically-conf...