AMPK and TOR: The Yin and Yang of Cellular Nutrient Sensing and Growth Control
The AMPK (AMP-activated protein kinase) and TOR (target-of-rapamycin) pathways are interlinked, opposing signaling pathways involved in sensing availability of nutrients and energy and regulation of cell growth. AMPK (Yin, or the “dark side”) is switched on by lack of energy or nutrients and inhibit...
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Published in | Cell metabolism Vol. 31; no. 3; pp. 472 - 492 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
United States
Elsevier Inc
03.03.2020
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Online Access | Get full text |
ISSN | 1550-4131 1932-7420 1932-7420 |
DOI | 10.1016/j.cmet.2020.01.015 |
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