Fibrinogen and tumors

• Published in: Frontiers in oncology Vol. 14; p. 1393599
• Main Authors: Wu, Xinyuan, Yu, Xiaomin, Chen, Cheng, Chen, Chenlu, Wang, Yuxin, Su, Dongyan, Zhu, Liqing
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 08.05.2024
• Subjects: angiogenesis; fibrinogen; metastasis; molecular pathway; Oncology; pro-inflammatory; tumor; molecular pathway; fibrinogen; metastasis; angiogenesis; tumor; pro-inflammatory

Elevated plasma fibrinogen (Fg) levels consistently correlate with an unfavorable prognosis in various tumor patient cohorts. Within the tumor microenvironment, aberrant deposition and expression of Fg have been consistently observed, interacting with multiple cellular receptors and thereby accentua...