KT2 alleviates ulcerative colitis by reducing Th17 cell differentiation through the miR-302c-5p/STAT3 axis - Gu, Dandan; Nan, Qiong; Miao, Yinglei; Yang, Hailong; Li, Maojuan; Ye, Yan; Miao, Jiarong (European journal of cell biology, 2022)
Keywords: Animals; Cell Differentiation; Colitis, Ulcerative - chemically induced; Colitis, Ulcerative - genetics; Colitis, Ulcerative - metabolism; Interleukin-17 - adverse effects; Interleukin-17 - metabolism; KT2; Mice; MicroRNAs - genetics; MicroRNAs - metabolism; miR-302c-5p; Signal transducer and activator of transcription 3; STAT3 Transcription Factor - genetics; STAT3 Transcription Factor - metabolism; Th17 cell differentiation; Th17 Cells - metabolism; Ulcerative colitis; MLNs; miRNAs; DSS; STAT3; qRT-PCR; KT2; mRNA; 3’UTR; IL-1β; DAI; MPO; UC; AMPs; Th17 cell differentiation; TNF-α; TJ; FBS; miR-302c-5p; Signal transducer and activator of transcription 3; IL-17; HE; WT; Ulcerative colitis; ELISA