A single-cell transcriptomic landscape of mouse testicular aging

• Published in: Journal of advanced research Vol. 53; pp. 219 - 234
• Main Authors: Zhang, Wei, Xia, Siyu, Xiao, Wei, Song, Yali, Tang, Li, Cao, Min, Yang, Jing, Wang, Shuang, Li, Zhijie, Xu, Chengchao, Liu, Jianqiao, Zhao, Shanchao, Yang, Chuanbin, Wang, Jigang
• Format: Journal Article
• Language: English
• Published: Egypt Elsevier B.V 01.11.2023; Elsevier
• Subjects: Aging; Inflammation; Senescence; Single-cell RNA sequencing; Testis; Testis; ScRNA-seq; Senescence; DEGs; PCNA; Single-cell RNA sequencing; ROS; Aging; Inflammation; FC

[Display omitted] •The first single-cell transcriptomic atlases of testes of young and old mice were constructed.•Revealed aging-associated heterogenous differentially expressed genes in mouse testes.•Discovered aging-associated dysregulation of multiple biological processes in mouse testes.•Aging d...