Significant decrease of saturation index in erythrocytes membrane from subjects with non-alcoholic fatty liver disease (NAFLD)

• Published in: Lipids in health and disease Vol. 16; no. 1; p. 160
• Main Authors: Notarnicola, Maria, Caruso, Maria Gabriella, Tutino, Valeria, Bonfiglio, Caterina, Cozzolongo, Raffaele, Giannuzzi, Vito, De Nunzio, Valentina, De Leonardis, Giampiero, Abbrescia, Daniela I., Franco, Isabella, Intini, Vincenza, Mirizzi, Antonella, Osella, Alberto R.
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 23.08.2017; BioMed Central
• Subjects: Adult; Analysis; Azotemia - blood; Body Mass Index; Cell membranes; Cholesterol, HDL - blood; Chromatography, Gas; Development and progression; Erythrocyte Membrane - metabolism; Fatty Acids - metabolism; Fatty liver; Female; Ferritins - blood; Humans; Insulin - blood; Liver - metabolism; Male; Middle Aged; Non-alcoholic Fatty Liver Disease - blood; Non-alcoholic Fatty Liver Disease - metabolism; Physiological aspects; Red blood cells; Triglycerides - blood; Italy; Erythrocyte membrane; Fatty acids profile; NAFLD; Lipidomic analysis; Saturation index

The lipidomic profiling of erythrocyte membranes is expected to provide a peculiar scenario at molecular level of metabolic and nutritional pathways which may influence the lipid balance and the adaptation and homeostasis of the organism. Considering that lipid accumulation in the cell is important...