Enzymatic Synthesis of Novel and Highly Soluble Puerarin Glucoside by Deinococcus geothermalis Amylosucrase

• Published in: Molecules (Basel, Switzerland) Vol. 27; no. 13; p. 4074
• Main Authors: Ding, Hsiou-Yu, Wang, Tzi-Yuan, Wu, Jiumn-Yih, Tsai, Yu-Li, Chang, Te-Sheng
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 24.06.2022; MDPI
• Subjects: Amylosucrase; Biotransformation; Daidzein; Deinococcus geothermalis; Enzymatic synthesis; Enzymes; Flavonoids; Glucosides; glycosylation; Leguminous plants; Pharmacology; puerarin; Solubility; Sucrose

Puerarin (daidzein-8-C-glucoside) is an isoflavone isolated from several leguminous plants of the genus Pueraria. Puerarin possesses several pharmacological properties; however, the poor solubility of puerarin limits its applications. To resolve this poor solubility, Deinococcus geothermalis amylosu...