Quantitative MRI findings indicate diffuse white matter damage in Susac Syndrome

• Published in: Multiple sclerosis journal - experimental, translational and clinical Vol. 8; no. 1; p. 20552173221078834
• Main Authors: Johnson, P, Chan, JK, Vavasour, IM, Abel, S, Lee, LE, Yong, H, Laule, C, Li, DKB, Tam, R, Traboulsee, A, Carruthers, RL, Kolind, SH
• Format: Journal Article
• Language: English
• Published: London, England SAGE Publications 01.01.2022; Sage Publications Ltd
• Subjects: Brain; Magnetic resonance imaging; Multiple sclerosis; Original; myelin water imaging; MRI; Susac syndrome; multiple sclerosis; demyelination; diffusion basis spectrum imaging; neuroimaging

Background Susac Syndrome (SuS) is an autoimmune endotheliopathy impacting the brain, retina and cochlea that can clinically mimic multiple sclerosis (MS). Objective To evaluate non-lesional white matter demyelination changes in SuS compared to MS and healthy controls (HC) using quantitative MRI. Me...