Integration of Metabolomics and Transcriptomics Reveals Major Metabolic Pathways and Potential Biomarkers Involved in Pulmonary Tuberculosis and Pulmonary Tuberculosis-Complicated Diabetes

• Published in: Microbiology spectrum Vol. 11; no. 4; p. e0057723
• Main Authors: Wang, Yunguang, He, Xinxin, Zheng, Danna, He, Qiang, Sun, Lifang, Jin, Juan
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 17.08.2023
• Subjects: diabetes mellitus; metabolomic; NOTCH1; pulmonary tuberculosis; transcriptome; pulmonary tuberculosis; metabolomic; diabetes mellitus; NOTCH1; transcriptome

The comorbidity of diabetes mellitus (DM) significantly increases the risk of tuberculosis infection and adverse tuberculosis treatment outcomes. Most previous studies have focused on the relationship between the effect of blood glucose control and the outcome of antituberculosis treatment in pulmon...