Minocycline vs. tetracycline in bismuth-containing quadruple therapy for Helicobacter pylori rescue treatment: a multicentre, randomized controlled trial

• Published in: Journal of gastroenterology Vol. 58; no. 7; pp. 633 - 641
• Main Authors: Huang, Yu, Chen, Jinnan, Ding, Zhaohui, Chen, Xi, Liang, Xiao, Zeng, Xin, Xu, Fei, Han, Yuehua, Lu, Hong
• Format: Journal Article
• Language: English
• Published: Singapore Springer Nature Singapore 01.07.2023; Springer; Springer Nature B.V
• Subjects: Abdominal Surgery; Amoxicillin - adverse effects; Anti-Bacterial Agents - adverse effects; Antibiotic resistance; Antibiotics; Biopsy; Bismuth - adverse effects; Breath tests; Care and treatment; Clinical trials; Colorectal Surgery; Compliance; Drug resistance; Drug resistance in microorganisms; Drug Therapy, Combination; Eradication; Gastroenterology; Helicobacter infections; Helicobacter Infections - drug therapy; Helicobacter pylori; Hepatology; Histology; Hospitals; Humans; Infections; Meals; Medicine; Medicine & Public Health; Metronidazole; Metronidazole - adverse effects; Minocycline; Minocycline - adverse effects; Omeprazole; Original Article—Alimentary Tract; Pharmaceutical industry; Proton Pump Inhibitors; Surgical Oncology; Tetracycline - adverse effects; Treatment Outcome; Urea; Minocycline; Rescue therapy; Tetracycline; Helicobacter pylori

Background To compare the efficacy and tolerability of minocycline vs. tetracycline in bismuth-containing quadruple therapy for Helicobacter pylori ( H. pylori ) rescue treatment. Methods This study was a multi-center, randomized-controlled, non-inferiority trial. Refractory H. pylori -infected subj...