Hubless keypoint-based 3D deformable groupwise registration
•The proposed groupwise registration does not use any reference image.•Only keypoints are extracted from the images, which results in a fast algorithm with low memory footprint, and robust to large deformation (e.g. for full-body registration).•An anatomical landmark-based benchmark shows that our a...
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Published in | Medical image analysis Vol. 59; p. 101564 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
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01.01.2020
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Abstract | •The proposed groupwise registration does not use any reference image.•Only keypoints are extracted from the images, which results in a fast algorithm with low memory footprint, and robust to large deformation (e.g. for full-body registration).•An anatomical landmark-based benchmark shows that our approach is similar or better than voxel-based approaches while being significantly faster and consuming less memory.
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We present a novel algorithm for Fast Registration Of image Groups (FROG), applied to large 3D image groups. Our approach extracts 3D SURF keypoints from images, computes matched pairs of keypoints and registers the group by minimizing pair distances in a hubless way i.e. without computing any central mean image. Using keypoints significantly reduces the problem complexity compared to voxel-based approaches, and enables us to provide an in-core global optimization, similar to the Bundle Adjustment for 3D reconstruction. As we aim to register images of different patients, the matching step yields many outliers. Then we propose a new EM-weighting algorithm which efficiently discards outliers. Global optimization is carried out with a fast gradient descent algorithm. This allows our approach to robustly register large datasets. The result is a set of diffeomorphic half transforms which link the volumes together and can be subsequently exploited for computational anatomy and landmark detection. We show experimental results on whole-body CT scans, with groups of up to 103 volumes. On a benchmark based on anatomical landmarks, our algorithm compares favorably with the star-groupwise voxel-based ANTs and NiftyReg approaches while being much faster. We also discuss the limitations of our approach for lower resolution images such as brain MRI. |
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AbstractList | •The proposed groupwise registration does not use any reference image.•Only keypoints are extracted from the images, which results in a fast algorithm with low memory footprint, and robust to large deformation (e.g. for full-body registration).•An anatomical landmark-based benchmark shows that our approach is similar or better than voxel-based approaches while being significantly faster and consuming less memory.
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We present a novel algorithm for Fast Registration Of image Groups (FROG), applied to large 3D image groups. Our approach extracts 3D SURF keypoints from images, computes matched pairs of keypoints and registers the group by minimizing pair distances in a hubless way i.e. without computing any central mean image. Using keypoints significantly reduces the problem complexity compared to voxel-based approaches, and enables us to provide an in-core global optimization, similar to the Bundle Adjustment for 3D reconstruction. As we aim to register images of different patients, the matching step yields many outliers. Then we propose a new EM-weighting algorithm which efficiently discards outliers. Global optimization is carried out with a fast gradient descent algorithm. This allows our approach to robustly register large datasets. The result is a set of diffeomorphic half transforms which link the volumes together and can be subsequently exploited for computational anatomy and landmark detection. We show experimental results on whole-body CT scans, with groups of up to 103 volumes. On a benchmark based on anatomical landmarks, our algorithm compares favorably with the star-groupwise voxel-based ANTs and NiftyReg approaches while being much faster. We also discuss the limitations of our approach for lower resolution images such as brain MRI. We present a novel algorithm for Fast Registration Of image Groups (FROG), applied to large 3D image groups. Our approach extracts 3D SURF keypoints from images, computes matched pairs of keypoints and registers the group by minimizing pair distances in a hubless way i.e. without computing any central mean image. Using keypoints significantly reduces the problem complexity compared to voxel-based approaches, and enables us to provide an in-core global optimization, similar to the Bundle Adjustment for 3D reconstruction. As we aim to register images of different patients, the matching step yields many outliers. Then we propose a new EM-weighting algorithm which efficiently discards outliers. Global optimization is carried out with a fast gradient descent algorithm. This allows our approach to robustly register large datasets. The result is a set of diffeomorphic half transforms which link the volumes together and can be subsequently exploited for computational anatomy and landmark detection. We show experimental results on whole-body CT scans, with groups of up to 103 volumes. On a benchmark based on anatomical landmarks, our algorithm compares favorably with the star-groupwise voxel-based ANTs and NiftyReg approaches while being much faster. We also discuss the limitations of our approach for lower resolution images such as brain MRI. We present a novel deformable groupwise registration method, applied to large 3D image groups. Our approach extracts 3D SURF keypoints from images, computes matched pairs of keypoints and registers the group by minimizing pair distances in a hubless way i.e. without computing any central mean image. Using keypoints significantly reduces the problem complexity compared to voxel-based approaches, and enables us to provide an in-core global optimization, similar to the Bundle Adjustment for 3D reconstruction. As we aim at registering images of different patients, the matching step yields many outliers. Then we propose a new EM-weighting algorithm which efficiently discards outliers. Global optimization is carried out with a fast gradient descent algorithm. This allows our approach to robustly register large datasets. The result is a set of half transforms which link the volumes together and can be subsequently exploited for computational anatomy, landmark detection or image segmentation. We show experimental results on whole-body CT scans, with groups of up to 103 volumes. On a benchmark based on anatomical landmarks, our algorithm compares favorably with the star-groupwise voxel-based ANTs and NiftyReg approaches while being much faster. We also discuss the limitations of our approach for lower resolution images such as brain MRI. |
ArticleNumber | 101564 |
Author | Agier, R. Kéchichian, R. Fanton, L. Valette, S. Prost, R. |
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Snippet | •The proposed groupwise registration does not use any reference image.•Only keypoints are extracted from the images, which results in a fast algorithm with low... We present a novel algorithm for Fast Registration Of image Groups (FROG), applied to large 3D image groups. Our approach extracts 3D SURF keypoints from... We present a novel deformable groupwise registration method, applied to large 3D image groups. Our approach extracts 3D SURF keypoints from images, computes... |
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SubjectTerms | Algorithms Bundle adjustment Computational neuroscience Computed tomography Computer Science Formability Global optimization Groupwise registration Image Processing Image reconstruction Keypoints Magnetic resonance imaging Medical imaging Outliers (statistics) Signal and Image Processing |
Title | Hubless keypoint-based 3D deformable groupwise registration |
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