Effect of parenteral glutamine supplementation combined with enteral nutrition on Hsp90 expression and lymphoid organ apoptosis in severely burned rats

• Published in: Burns Vol. 42; no. 7; pp. 1494 - 1506
• Main Authors: Fan, Jun, Wu, Jing, Wu, Li-dong, Li, Guo-ping, Xiong, Meng, Chen, Xi, Meng, Qing-yan
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.11.2016
• Subjects: Administration, Intravenous; Animals; Apoptosis; Apoptosis - drug effects; Blotting, Western; Burn; Burns - therapy; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes - cytology; CD4-Positive T-Lymphocytes - drug effects; CD8-Positive T-Lymphocytes - cytology; CD8-Positive T-Lymphocytes - drug effects; Chromatography, High Pressure Liquid; Critical Care; Dietary Supplements; Enteral Nutrition; Flow Cytometry; Glutamine - pharmacology; Hsp; HSP90 Heat-Shock Proteins - drug effects; HSP90 Heat-Shock Proteins - metabolism; Immunity; In Situ Nick-End Labeling; Lymphocyte Count; Male; Muscle, Skeletal - drug effects; Muscle, Skeletal - metabolism; Parenteral glutamine supplementation; Phagocytosis - drug effects; Rats; Rats, Sprague-Dawley; Spleen - drug effects; Spleen - metabolism; T-Lymphocytes - cytology; T-Lymphocytes - drug effects; Thymus Gland - drug effects; Thymus Gland - metabolism; Parenteral glutamine supplementation; Burn; Enteral nutrition; Hsp; Immunity; Apoptosis

•We studied the effects of glutamine combined with enteral nutrition on immune function in burned rats.•Glutamine combined with enteral nutrition enhanced Hsp90 expression in lymphatic organs in burned rats.•Glutamine combined with enteral nutrition attenuated lymphatic organ apoptosis in burned rat...