Peroxidation of n-3 and n-6 polyunsaturated fatty acids in the acidic tumor environment leads to ferroptosis-mediated anticancer effects - Dierge, Emeline; Debock, Elena; Guilbaud, Céline; Corbet, Cyril; Mignolet, Eric; Mignard, Louise; Bastien, Estelle; Dessy, Chantal; Larondelle, Yvan; Feron, Olivier (Cell metabolism, 2021)
Keywords: acidosis; Animals; cancer; diacylglycerol acyltransferase; docosahexaenoic acid; Fatty Acids; Fatty Acids, Omega-3 - pharmacology; Fatty Acids, Omega-6 - pharmacology; Fatty Acids, Unsaturated - metabolism; Ferroptosis; lipid droplets; Mice; Neoplasms - drug therapy; peroxidation; polyunsaturated fatty acids; spheroids; ferroptosis; fatty acids; peroxidation; diacylglycerol acyltransferase; acidosis; docosahexaenoic acid; polyunsaturated fatty acids; cancer; lipid droplets; spheroids