Viral Ubiquitin Ligase Stimulates Selective Host MicroRNA Expression by Targeting ZEB Transcriptional Repressors - Lutz, Gabriel; Jurak, Igor; Kim, Eui Tae; Kim, Ju Youn; Hackenberg, Michael; Leader, Andrew; Stoller, Michelle L.; Fekete, Donna M.; Weitzman, Matthew D.; Coen, Donald M.; Wilson, Angus C. (Viruses, 2017)
Keywords: Cell Nucleus; Cells, Cultured; Crystallin; E3 ubiquitin ligase; Fibroblasts; Fibroblasts - virology; Gene expression; Gene Expression Regulation; Herpes simplex; herpes simplex virus; Herpesvirus 1, Human - enzymology; Herpesvirus 1, Human - genetics; Homeobox; host shutoff; Host-Pathogen Interactions; HSV-1; Humans; ICP0; Immediate-Early Proteins - deficiency; Immediate-Early Proteins - genetics; Kinases; microRNA; MicroRNAs - genetics; miR-182; miR-183; miR-96; miRNA; mRNA stability; Nerve Tissue Proteins - genetics; Neurons - virology; Non-coding RNA; Protein Binding; Proteolysis; Repressors; RNA-Binding Proteins - genetics; Smad protein; Transcription factors; Ubiquitin; Ubiquitin-protein ligase; Ubiquitin-Protein Ligases - deficiency; Ubiquitin-Protein Ligases - genetics; Ubiquitin-Protein Ligases - metabolism; Virus Replication; ZEB; Zinc Finger E-box-Binding Homeobox 1 - genetics; Zinc Finger E-box-Binding Homeobox 1 - metabolism; Zinc finger proteins; herpes simplex virus; HSV-1; host shutoff; ZEB; ICP0; miR-182; miR-183; miR-96; microRNA; E3 ubiquitin ligase