Effects of COVID-19 Mental Health Interventions Among Children, Adolescents, and Adults Not Quarantined or Undergoing Treatment Due to COVID-19 Infection: A Systematic Review of Randomised Controlled Trials
Objectives Our objective was to assess the effects of mental health interventions for children, adolescents, and adults not quarantined or undergoing treatment due to COVID-19 infection. Methods We searched 9 databases (2 Chinese-language) from December 31, 2019, to March 22, 2021. We included rando...
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| Published in | Canadian journal of psychiatry Vol. 67; no. 5; pp. 336 - 350 |
|---|---|
| Main Authors | , , , , , , , , , , , , , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Los Angeles, CA
SAGE Publications
01.05.2022
SAGE PUBLICATIONS, INC |
| Subjects | |
| Online Access | Get full text |
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| Abstract | Objectives
Our objective was to assess the effects of mental health interventions for children, adolescents, and adults not quarantined or undergoing treatment due to COVID-19 infection.
Methods
We searched 9 databases (2 Chinese-language) from December 31, 2019, to March 22, 2021. We included randomised controlled trials of interventions to address COVID-19 mental health challenges among people not hospitalised or quarantined due to COVID-19 infection. We synthesized results descriptively due to substantial heterogeneity of populations and interventions and risk of bias concerns.
Results
We identified 9 eligible trials, including 3 well-conducted, well-reported trials that tested interventions designed specifically for COVID-19 mental health challenges, plus 6 other trials with high risk of bias and reporting concerns, all of which tested standard interventions (e.g., individual or group therapy, expressive writing, mindfulness recordings) minimally adapted or not specifically adapted for COVID-19. Among the 3 well-conducted and reported trials, 1 (N = 670) found that a self-guided, internet-based cognitive-behavioural intervention targeting dysfunctional COVID-19 worry significantly reduced COVID-19 anxiety (standardized mean difference [SMD] 0.74, 95% confidence interval [CI], 0.58 to 0.90) and depression symptoms (SMD 0.38, 95% CI, 0.22 to 0.55) in Swedish general population participants. A lay-delivered telephone intervention for homebound older adults in the United States (N = 240) and a peer-moderated education and support intervention for people with a rare autoimmune condition from 12 countries (N = 172) significantly improved anxiety (SMD 0.35, 95% CI, 0.09 to 0.60; SMD 0.31, 95% CI, 0.03 to 0.58) and depressive symptoms (SMD 0.31, 95% CI, 0.05 to 0.56; SMD 0.31, 95% CI, 0.07 to 0.55) 6-week post-intervention, but these were not significant immediately post-intervention. No trials in children or adolescents were identified.
Conclusions
Interventions that adapt evidence-based strategies for feasible delivery may be effective to address mental health in COVID-19. More well-conducted trials, including for children and adolescents, are needed. |
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| AbstractList | Objectives Our objective was to assess the effects of mental health interventions for children, adolescents, and adults not quarantined or undergoing treatment due to COVID-19 infection. Methods We searched 9 databases (2 Chinese-language) from December 31, 2019, to March 22, 2021. We included randomised controlled trials of interventions to address COVID-19 mental health challenges among people not hospitalised or quarantined due to COVID-19 infection. We synthesized results descriptively due to substantial heterogeneity of populations and interventions and risk of bias concerns. Results We identified 9 eligible trials, including 3 well-conducted, well-reported trials that tested interventions designed specifically for COVID-19 mental health challenges, plus 6 other trials with high risk of bias and reporting concerns, all of which tested standard interventions (e.g., individual or group therapy, expressive writing, mindfulness recordings) minimally adapted or not specifically adapted for COVID-19. Among the 3 well-conducted and reported trials, 1 (N = 670) found that a self-guided, internet-based cognitive-behavioural intervention targeting dysfunctional COVID-19 worry significantly reduced COVID-19 anxiety (standardized mean difference [SMD] 0.74, 95% confidence interval [CI], 0.58 to 0.90) and depression symptoms (SMD 0.38, 95% CI, 0.22 to 0.55) in Swedish general population participants. A lay-delivered telephone intervention for homebound older adults in the United States (N = 240) and a peer-moderated education and support intervention for people with a rare autoimmune condition from 12 countries (N = 172) significantly improved anxiety (SMD 0.35, 95% CI, 0.09 to 0.60; SMD 0.31, 95% CI, 0.03 to 0.58) and depressive symptoms (SMD 0.31, 95% CI, 0.05 to 0.56; SMD 0.31, 95% CI, 0.07 to 0.55) 6-week post-intervention, but these were not significant immediately post-intervention. No trials in children or adolescents were identified. Conclusions Interventions that adapt evidence-based strategies for feasible delivery may be effective to address mental health in COVID-19. More well-conducted trials, including for children and adolescents, are needed. Our objective was to assess the effects of mental health interventions for children, adolescents, and adults not quarantined or undergoing treatment due to COVID-19 infection. We searched 9 databases (2 Chinese-language) from December 31, 2019, to March 22, 2021. We included randomised controlled trials of interventions to address COVID-19 mental health challenges among people not hospitalised or quarantined due to COVID-19 infection. We synthesized results descriptively due to substantial heterogeneity of populations and interventions and risk of bias concerns. We identified 9 eligible trials, including 3 well-conducted, well-reported trials that tested interventions designed specifically for COVID-19 mental health challenges, plus 6 other trials with high risk of bias and reporting concerns, all of which tested standard interventions (e.g., individual or group therapy, expressive writing, mindfulness recordings) minimally adapted or not specifically adapted for COVID-19. Among the 3 well-conducted and reported trials, 1 ( = 670) found that a self-guided, internet-based cognitive-behavioural intervention targeting dysfunctional COVID-19 worry significantly reduced COVID-19 anxiety (standardized mean difference [SMD] 0.74, 95% confidence interval [CI], 0.58 to 0.90) and depression symptoms (SMD 0.38, 95% CI, 0.22 to 0.55) in Swedish general population participants. A lay-delivered telephone intervention for homebound older adults in the United States ( = 240) and a peer-moderated education and support intervention for people with a rare autoimmune condition from 12 countries ( = 172) significantly improved anxiety (SMD 0.35, 95% CI, 0.09 to 0.60; SMD 0.31, 95% CI, 0.03 to 0.58) and depressive symptoms (SMD 0.31, 95% CI, 0.05 to 0.56; SMD 0.31, 95% CI, 0.07 to 0.55) 6-week post-intervention, but these were not significant immediately post-intervention. No trials in children or adolescents were identified. Interventions that adapt evidence-based strategies for feasible delivery may be effective to address mental health in COVID-19. More well-conducted trials, including for children and adolescents, are needed. Our objective was to assess the effects of mental health interventions for children, adolescents, and adults not quarantined or undergoing treatment due to COVID-19 infection.OBJECTIVESOur objective was to assess the effects of mental health interventions for children, adolescents, and adults not quarantined or undergoing treatment due to COVID-19 infection.We searched 9 databases (2 Chinese-language) from December 31, 2019, to March 22, 2021. We included randomised controlled trials of interventions to address COVID-19 mental health challenges among people not hospitalised or quarantined due to COVID-19 infection. We synthesized results descriptively due to substantial heterogeneity of populations and interventions and risk of bias concerns.METHODSWe searched 9 databases (2 Chinese-language) from December 31, 2019, to March 22, 2021. We included randomised controlled trials of interventions to address COVID-19 mental health challenges among people not hospitalised or quarantined due to COVID-19 infection. We synthesized results descriptively due to substantial heterogeneity of populations and interventions and risk of bias concerns.We identified 9 eligible trials, including 3 well-conducted, well-reported trials that tested interventions designed specifically for COVID-19 mental health challenges, plus 6 other trials with high risk of bias and reporting concerns, all of which tested standard interventions (e.g., individual or group therapy, expressive writing, mindfulness recordings) minimally adapted or not specifically adapted for COVID-19. Among the 3 well-conducted and reported trials, 1 (N = 670) found that a self-guided, internet-based cognitive-behavioural intervention targeting dysfunctional COVID-19 worry significantly reduced COVID-19 anxiety (standardized mean difference [SMD] 0.74, 95% confidence interval [CI], 0.58 to 0.90) and depression symptoms (SMD 0.38, 95% CI, 0.22 to 0.55) in Swedish general population participants. A lay-delivered telephone intervention for homebound older adults in the United States (N = 240) and a peer-moderated education and support intervention for people with a rare autoimmune condition from 12 countries (N = 172) significantly improved anxiety (SMD 0.35, 95% CI, 0.09 to 0.60; SMD 0.31, 95% CI, 0.03 to 0.58) and depressive symptoms (SMD 0.31, 95% CI, 0.05 to 0.56; SMD 0.31, 95% CI, 0.07 to 0.55) 6-week post-intervention, but these were not significant immediately post-intervention. No trials in children or adolescents were identified.RESULTSWe identified 9 eligible trials, including 3 well-conducted, well-reported trials that tested interventions designed specifically for COVID-19 mental health challenges, plus 6 other trials with high risk of bias and reporting concerns, all of which tested standard interventions (e.g., individual or group therapy, expressive writing, mindfulness recordings) minimally adapted or not specifically adapted for COVID-19. Among the 3 well-conducted and reported trials, 1 (N = 670) found that a self-guided, internet-based cognitive-behavioural intervention targeting dysfunctional COVID-19 worry significantly reduced COVID-19 anxiety (standardized mean difference [SMD] 0.74, 95% confidence interval [CI], 0.58 to 0.90) and depression symptoms (SMD 0.38, 95% CI, 0.22 to 0.55) in Swedish general population participants. A lay-delivered telephone intervention for homebound older adults in the United States (N = 240) and a peer-moderated education and support intervention for people with a rare autoimmune condition from 12 countries (N = 172) significantly improved anxiety (SMD 0.35, 95% CI, 0.09 to 0.60; SMD 0.31, 95% CI, 0.03 to 0.58) and depressive symptoms (SMD 0.31, 95% CI, 0.05 to 0.56; SMD 0.31, 95% CI, 0.07 to 0.55) 6-week post-intervention, but these were not significant immediately post-intervention. No trials in children or adolescents were identified.Interventions that adapt evidence-based strategies for feasible delivery may be effective to address mental health in COVID-19. More well-conducted trials, including for children and adolescents, are needed.CONCLUSIONSInterventions that adapt evidence-based strategies for feasible delivery may be effective to address mental health in COVID-19. More well-conducted trials, including for children and adolescents, are needed. Objectives Our objective was to assess the effects of mental health interventions for children, adolescents, and adults not quarantined or undergoing treatment due to COVID-19 infection. Methods We searched 9 databases (2 Chinese-language) from December 31, 2019, to March 22, 2021. We included randomised controlled trials of interventions to address COVID-19 mental health challenges among people not hospitalised or quarantined due to COVID-19 infection. We synthesized results descriptively due to substantial heterogeneity of populations and interventions and risk of bias concerns. Results We identified 9 eligible trials, including 3 well-conducted, well-reported trials that tested interventions designed specifically for COVID-19 mental health challenges, plus 6 other trials with high risk of bias and reporting concerns, all of which tested standard interventions (e.g., individual or group therapy, expressive writing, mindfulness recordings) minimally adapted or not specifically adapted for COVID-19. Among the 3 well-conducted and reported trials, 1 (N = 670) found that a self-guided, internet-based cognitive-behavioural intervention targeting dysfunctional COVID-19 worry significantly reduced COVID-19 anxiety (standardized mean difference [SMD] 0.74, 95% confidence interval [CI], 0.58 to 0.90) and depression symptoms (SMD 0.38, 95% CI, 0.22 to 0.55) in Swedish general population participants. A lay-delivered telephone intervention for homebound older adults in the United States (N = 240) and a peer-moderated education and support intervention for people with a rare autoimmune condition from 12 countries (N = 172) significantly improved anxiety (SMD 0.35, 95% CI, 0.09 to 0.60; SMD 0.31, 95% CI, 0.03 to 0.58) and depressive symptoms (SMD 0.31, 95% CI, 0.05 to 0.56; SMD 0.31, 95% CI, 0.07 to 0.55) 6-week post-intervention, but these were not significant immediately post-intervention. No trials in children or adolescents were identified. Conclusions Interventions that adapt evidence-based strategies for feasible delivery may be effective to address mental health in COVID-19. More well-conducted trials, including for children and adolescents, are needed. |
| Author | Sun, Ying Fahim, Christine Agic, Branka Dal Santo, Tiffany Thombs, Brett D. Jiang, Xiaowen Wu, Yin Martin, Michael S. Markham, Sarah Rice, Danielle B. Sockalingam, Sanjeev Thombs-Vite, Ian Yao, Anneke Krishnan, Ankur Azar, Marleine Bonardi, Olivia Tasleem, Amina Wang, Yutong Li, Kexin Benedetti, Andrea Boruff, Jill T. He, Chen Turecki, Gustavo |
| AuthorAffiliation | 5 Department of Psychology, 5620 McGill University , Montreal, Quebec, Canada 2 Department of Psychiatry, 5620 McGill University , Montreal, Quebec, Canada 7 Dalla Lana School of Public Health, 7938 University of Toronto , Toronto, Ontario, Canada 16 Department of Educational and Counselling Psychology, 5620 McGill University , Montreal, Quebec, Canada 9 School of Epidemiology and Public Health, University of Ottawa, Ontario, Canada 12 McGill Group for Suicide Studies, Douglas Mental Health University Institute, 5620 McGill University , Montreal, Quebec, Canada 4 Department of Biostatistics and Health Informatics, King's College London, London, United Kingdom 11 149914 Department of Psychiatry , 7938 University of Toronto , Toronto, Ontario, Canada 10 Correctional Service of Canada, Ottawa, Ontario, Canada 8 Li Ka Shing Knowledge Institute, Unity Health Toronto, Toronto, Ontario, Canada 14 Department of Medicine, 5620 McGill University , Montreal, Quebec, Canada 13 Department of Epidemiology, Bio |
| AuthorAffiliation_xml | – name: 13 Department of Epidemiology, Biostatistics, and Occupational Health, 5620 McGill University , Montreal, Quebec, Canada – name: 7 Dalla Lana School of Public Health, 7938 University of Toronto , Toronto, Ontario, Canada – name: 3 Schulich Library of Physical Sciences, Life Sciences, and Engineering, 5620 McGill University , Montreal, Quebec, Canada – name: 16 Department of Educational and Counselling Psychology, 5620 McGill University , Montreal, Quebec, Canada – name: 11 149914 Department of Psychiatry , 7938 University of Toronto , Toronto, Ontario, Canada – name: 2 Department of Psychiatry, 5620 McGill University , Montreal, Quebec, Canada – name: 14 Department of Medicine, 5620 McGill University , Montreal, Quebec, Canada – name: 6 7978 Centre for Addiction and Mental Health , Toronto, Ontario, Canada – name: 10 Correctional Service of Canada, Ottawa, Ontario, Canada – name: 8 Li Ka Shing Knowledge Institute, Unity Health Toronto, Toronto, Ontario, Canada – name: 4 Department of Biostatistics and Health Informatics, King's College London, London, United Kingdom – name: 12 McGill Group for Suicide Studies, Douglas Mental Health University Institute, 5620 McGill University , Montreal, Quebec, Canada – name: 5 Department of Psychology, 5620 McGill University , Montreal, Quebec, Canada – name: 15 Respiratory Epidemiology and Clinical Research Unit, 5620 McGill University Health Centre , Montreal, Quebec, Canada – name: 17 Biomedical Ethics Unit, 5620 McGill University , Montreal, Quebec, Canada – name: 1 113635 Lady Davis Institute for Medical Research , Jewish General Hospital, Montreal, Quebec, Canada – name: 9 School of Epidemiology and Public Health, University of Ottawa, Ontario, Canada |
| Author_xml | – sequence: 1 givenname: Olivia surname: Bonardi fullname: Bonardi, Olivia – sequence: 2 givenname: Yutong surname: Wang fullname: Wang, Yutong – sequence: 3 givenname: Kexin surname: Li fullname: Li, Kexin – sequence: 4 givenname: Xiaowen surname: Jiang fullname: Jiang, Xiaowen – sequence: 5 givenname: Ankur surname: Krishnan fullname: Krishnan, Ankur – sequence: 6 givenname: Chen surname: He fullname: He, Chen – sequence: 7 givenname: Ying surname: Sun fullname: Sun, Ying – sequence: 8 givenname: Yin surname: Wu fullname: Wu, Yin – sequence: 9 givenname: Jill T. surname: Boruff fullname: Boruff, Jill T. – sequence: 10 givenname: Sarah surname: Markham fullname: Markham, Sarah – sequence: 11 givenname: Danielle B. surname: Rice fullname: Rice, Danielle B. – sequence: 12 givenname: Ian surname: Thombs-Vite fullname: Thombs-Vite, Ian – sequence: 13 givenname: Amina surname: Tasleem fullname: Tasleem, Amina – sequence: 14 givenname: Tiffany surname: Dal Santo fullname: Dal Santo, Tiffany – sequence: 15 givenname: Anneke surname: Yao fullname: Yao, Anneke – sequence: 16 givenname: Marleine surname: Azar fullname: Azar, Marleine – sequence: 17 givenname: Branka surname: Agic fullname: Agic, Branka – sequence: 18 givenname: Christine surname: Fahim fullname: Fahim, Christine – sequence: 19 givenname: Michael S. orcidid: 0000-0002-5056-618X surname: Martin fullname: Martin, Michael S. – sequence: 20 givenname: Sanjeev surname: Sockalingam fullname: Sockalingam, Sanjeev – sequence: 21 givenname: Gustavo surname: Turecki fullname: Turecki, Gustavo – sequence: 22 givenname: Andrea surname: Benedetti fullname: Benedetti, Andrea – sequence: 23 givenname: Brett D. orcidid: 0000-0002-5644-8432 surname: Thombs fullname: Thombs, Brett D. email: brett.thombs@mcgill.ca |
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Our objective was to assess the effects of mental health interventions for children, adolescents, and adults not quarantined or undergoing treatment... Our objective was to assess the effects of mental health interventions for children, adolescents, and adults not quarantined or undergoing treatment due to... Objectives Our objective was to assess the effects of mental health interventions for children, adolescents, and adults not quarantined or undergoing treatment... |
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| SubjectTerms | Adolescent Aged Anxiety - etiology Anxiety - therapy Child Coronaviruses COVID-19 COVID-19 - complications COVID-19 - psychology COVID-19 - therapy Depression - etiology Depression - therapy Humans Infections Intervention Mental Health Quarantine Quarantine - psychology Randomized Controlled Trials as Topic Systematic Review Teenagers |
| Title | Effects of COVID-19 Mental Health Interventions Among Children, Adolescents, and Adults Not Quarantined or Undergoing Treatment Due to COVID-19 Infection: A Systematic Review of Randomised Controlled Trials |
| URI | https://journals.sagepub.com/doi/full/10.1177/07067437211070648 https://www.ncbi.nlm.nih.gov/pubmed/35275494 https://www.proquest.com/docview/2657694094 https://www.proquest.com/docview/2638716733 https://pubmed.ncbi.nlm.nih.gov/PMC9065490 |
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