Hemochromatosis gene mutations, liver function tests and iron status in alcohol-dependent patients admitted for detoxification

• Published in: Journal of gastroenterology and hepatology Vol. 22; no. 6; pp. 852 - 854
• Main Authors: Robinson, Geoffrey, Narasimhan, Seshasayee, Weatherall, Mark, Beasley, Richard
• Format: Journal Article
• Language: English
• Published: Melbourne, Australia Blackwell Publishing Asia 01.06.2007; Blackwell Science
• Subjects: Addictive behaviors; Adult and adolescent clinical studies; Alcoholism; Alcoholism and acute alcohol poisoning; Analysis of Variance; Biological and medical sciences; Chi-Square Distribution; Female; Genetic Predisposition to Disease; genetics; hemochromatosis; Hemochromatosis - genetics; Humans; Inactivation, Metabolic; Iron - analysis; iron status; Liver Diseases, Alcoholic - genetics; Liver Diseases, Alcoholic - rehabilitation; Liver Function Tests; Male; Medical sciences; Metabolic diseases; Metals (hemochromatosis...); Middle Aged; Mutation; mutations; Other metabolic disorders; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Risk Factors; Toxicology; New Zealand; Oceania; Human; Iron overload; Hemochromatosis; Alcoholism; Detoxification; Metabolic diseases; Alcohol; Hepatic disease; Iron; Enzymopathy; iron status; Liver function; mutations; Digestive diseases; Genetics; liver function tests; Mutation

Background:  Screening of target populations for hemochromatosis (HFE) gene allele status has been recommended. Alcoholic liver disease may be associated with iron overload and there is evidence of excessive alcohol consumption among patients with hereditary hemochromatosis. This study determined th...