Analysis of the association of polymorphism in the osteoprotegerin gene with susceptibility to chronic kidney disease and periodontitis

• Published in: Journal of periodontal research Vol. 43; no. 5; pp. 578 - 584
• Main Authors: Baioni, C. S., De Souza, C. M., Ribeiro Braosi, A. P., Luczyszyn, S. M., Dias da Silva, M. A., Ignácio, S. A., Naval Machado, M. Â., Benato Martins, W. D., Riella, M. C., Pecoits-Filho, R., Trevilatto, P. C.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.10.2008; Blackwell
• Subjects: Adult; Aged; Biological and medical sciences; Brazil; chronic kidney disease; Dentistry; Facial bones, jaws, teeth, parodontium: diseases, semeiology; Female; Gene Frequency; genetic polymorphism; Genetic Predisposition to Disease; Humans; Kidney Failure, Chronic - genetics; Kidneys; Male; Medical sciences; Middle Aged; Nephrology. Urinary tract diseases; Nephropathies. Renovascular diseases. Renal failure; Non tumoral diseases; osteoprotegerin; Osteoprotegerin - genetics; Otorhinolaryngology. Stomatology; periodontal disease; Periodontitis - genetics; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Renal failure; Urinary system involvement in other diseases. Miscellaneous; Young Adult; Brazil; Kidney disease; Urinary system disease; Stomatology; Chronic kidney disease; Osteoprotegerin; Periodontal disease; Sensitivity; Association; Gene; Periodontitis; Renal failure; Genetics; genetic polymorphism; Polymorphism

Background and Objective:  Chronic kidney disease (CKD) is a complex disorder, which results in several complications involving disturbance of mineral metabolism. Periodontal disease is an infectious disease that appears to be an important cause of systemic inflammation in CKD patients. Periodontal...