Pharmacokinetics, pharmacodynamics, and safety of peginterferon beta‐1a in subjects with normal or impaired renal function - Hu, Xiao; Seddighzadeh, Ali; Stecher, Scott; Zhu, Ying; Goyal, Jaya; Matson, Mark; Marbury, Thomas; Smith, William; Nestorov, Ivan; Hung, Serena (Journal of clinical pharmacology, 2015)
Keywords: Adult; Aged; Antibodies - blood; clinical trial; Female; Humans; Interferon-beta - adverse effects; Interferon-beta - blood; Interferon-beta - pharmacokinetics; Interferon-beta - pharmacology; Male; Middle Aged; Models, Biological; multiple sclerosis; Neopterin - blood; pegylation; Polyethylene Glycols - adverse effects; Polyethylene Glycols - pharmacokinetics; Polyethylene Glycols - pharmacology; Renal Insufficiency - blood; Renal Insufficiency - metabolism; clinical trial; pegylation; multiple sclerosis