Competitive inhibition of the 5-lipoxygenase-catalysed linoleate oxidation by arachidonic and 5-hydroperoxy-eicosatetraenoic acids
Linoleic and arachidonic acids are competing substrates for 5-1ipoxygenase from barley. When these two substrates are added simultaneously, arachidonic acid acts as a competitive inhibitor of linoleic acid oxidation with K i of 20 μM, the same value as the Michaelis constant for arachidonate oxygena...
Saved in:
Published in | FEBS letters Vol. 377; no. 3; pp. 306 - 308 |
---|---|
Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
England
Elsevier B.V
27.12.1995
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Be the first to leave a comment!