Fish oil and fenofibrate for the treatment of hypertriglyceridemia in HIV-infected subjects on antiretroviral therapy: results of ACTG A5186

• Published in: Journal of acquired immune deficiency syndromes (1999) Vol. 47; no. 4; p. 459
• Main Authors: Gerber, John G, Kitch, Douglas W, Fichtenbaum, Carl J, Zackin, Robert A, Charles, Stéphannie, Hogg, Evelyn, Acosta, Edward P, Connick, Elizabeth, Wohl, David, Kojic, E Milu, Benson, Constance A, Aberg, Judith A
• Format: Journal Article
• Language: English
• Published: United States 01.04.2008
• Subjects: Adult; Cholesterol, HDL - blood; Cholesterol, LDL - blood; Drug Therapy, Combination; Female; Fenofibrate - therapeutic use; Fish Oils - therapeutic use; HIV Infections - blood; HIV Infections - complications; HIV Infections - drug therapy; Humans; Hypertriglyceridemia - blood; Hypertriglyceridemia - complications; Hypertriglyceridemia - drug therapy; Hypolipidemic Agents - therapeutic use; Male; Middle Aged; Time Factors; Treatment Outcome; Triglycerides - blood

Fish oil has been shown to reduce serum triglyceride (TG) concentrations. In HIV-infected patients on antiretroviral therapy, high TG concentrations likely contribute to increased risk of cardiovascular disease. AIDS Clinical Trials Group A5186 examined the safety and efficacy of fish oil plus fenof...