Association of peptidoglycan recognition protein 1 to post‐myocardial infarction and periodontal inflammation: A subgroup report from the PAROKRANK (Periodontal Disease and the Relation to Myocardial Infarction) study

• Published in: Journal of periodontology (1970) Vol. 93; no. 9; pp. 1325 - 1335
• Main Authors: Rathnayake, Nilminie, Gustafsson, Anders, Sorsa, Timo, Norhammar, Anna, Bostanci, Nagihan
• Format: Journal Article
• Language: English
• Published: United States 01.09.2022
• Subjects: Biomarkers; Carrier Proteins; Humans; IL‐1β; Inflammation; Interleukin-1beta; Matrix Metalloproteinase 8 - metabolism; MMP‐8; myocardial infarction; Myocardial Infarction - complications; Periodontal Diseases; periodontitis; PGLYRP1; saliva; Saliva - metabolism; TREM‐1; Triggering Receptor Expressed on Myeloid Cells-1; saliva; TREM-1; myocardial infarction; periodontitis; MMP-8; IL-1β; PGLYRP1

Background Peptidoglycan recognition protein 1 (PGLYRP1) is an antimicrobial and proinflammatory innate immunity protein activated during infections. We aimed to investigate whether PGYLRP1 and associated molecules of the immune response in saliva is a cumulative outcome result of both MI and period...