MicroRNA-455-3p promotes invasion and migration in triple negative breast cancer by targeting tumor suppressor EI24

• Published in: Oncotarget Vol. 8; no. 12; pp. 19455 - 19466
• Main Authors: Li, Zhishuang, Meng, Qingyong, Pan, Aifeng, Wu, Xiaojuan, Cui, Jingjing, Wang, Yan, Li, Li
• Format: Journal Article
• Language: English
• Published: United States Impact Journals LLC 21.03.2017
• Subjects: 3' Untranslated Regions - genetics; Apoptosis; Apoptosis Regulatory Proteins - genetics; Apoptosis Regulatory Proteins - metabolism; Biomarkers, Tumor - genetics; Biomarkers, Tumor - metabolism; Carcinoma, Ductal, Breast - genetics; Carcinoma, Ductal, Breast - metabolism; Carcinoma, Ductal, Breast - pathology; Cell Movement; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs - genetics; Neoplasm Invasiveness; Neoplasm Staging; Nuclear Proteins - genetics; Nuclear Proteins - metabolism; Prognosis; Research Paper; Triple Negative Breast Neoplasms - genetics; Triple Negative Breast Neoplasms - metabolism; Triple Negative Breast Neoplasms - pathology; Tumor Cells, Cultured; migration; miR455-3p; triple negative breast cancer; invasion; EI24

Lacking of treatment methods for the patients with triple negative breast cancer (TNBC) underscores the pivotal needs to further understand its biology as well as to find better biomarkers and develop novel therapeutic strategies. Increasing evidences support that aberrantly expressed microRNAs (miR...