Development and initial performance of a miniature axial flow blood pump using magnetic fluid shaft seal
In this study, we developed a new catheter-mounted micro-axial flow blood pump (MFBP) using a new miniature magnetic fluid shaft seal (MFSS). The prototype of the catheter-mounted MFBP had a maximum diameter of 8 mm and a length of 50 mm. The new MFSS composed a neodymium magnet ring, an iron ring,...
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Published in | Journal of artificial organs Vol. 26; no. 1; pp. 12 - 16 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
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Singapore
Springer Nature Singapore
01.03.2023
Springer Nature B.V |
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Abstract | In this study, we developed a new catheter-mounted micro-axial flow blood pump (MFBP) using a new miniature magnetic fluid shaft seal (MFSS). The prototype of the catheter-mounted MFBP had a maximum diameter of 8 mm and a length of 50 mm. The new MFSS composed a neodymium magnet ring, an iron ring, and a magnetic fluid particularly designed for the MFSS. The new MFSS had outer and inner diameters of 4.0 mm and 2.6 mm, respectively, and a length of 3.0 mm. The sealing pressure of the MFSS was calculated to be 432 mmHg using FEM (Finite Element Method) result; therefore, the MFSS had sufficient sealing pressure for the catheter-mounted MFBP. The friction loss of the MFSS included the friction owing to the viscosity of the magnetic fluid and the magnetic force between the iron ring and ring magnet. The total friction loss of the MFSS was 0.08–0.09 W in the pump operational speed range from 22,000 to 35,000 rpm. From the in vitro experimental results, the catheter-mounted MFBP using the MFSS had a pump output of 3 L/min. against a differential pressure of 60 mmHg, and the pump characteristics of the MFBP were almost the same as those of Impella 5.0. |
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AbstractList | In this study, we developed a new catheter-mounted micro-axial flow blood pump (MFBP) using a new miniature magnetic fluid shaft seal (MFSS). The prototype of the catheter-mounted MFBP had a maximum diameter of 8 mm and a length of 50 mm. The new MFSS composed a neodymium magnet ring, an iron ring, and a magnetic fluid particularly designed for the MFSS. The new MFSS had outer and inner diameters of 4.0 mm and 2.6 mm, respectively, and a length of 3.0 mm. The sealing pressure of the MFSS was calculated to be 432 mmHg using FEM (Finite Element Method) result; therefore, the MFSS had sufficient sealing pressure for the catheter-mounted MFBP. The friction loss of the MFSS included the friction owing to the viscosity of the magnetic fluid and the magnetic force between the iron ring and ring magnet. The total friction loss of the MFSS was 0.08–0.09 W in the pump operational speed range from 22,000 to 35,000 rpm. From the in vitro experimental results, the catheter-mounted MFBP using the MFSS had a pump output of 3 L/min. against a differential pressure of 60 mmHg, and the pump characteristics of the MFBP were almost the same as those of Impella 5.0. In this study, we developed a new catheter-mounted micro-axial flow blood pump (MFBP) using a new miniature magnetic fluid shaft seal (MFSS). The prototype of the catheter-mounted MFBP had a maximum diameter of 8 mm and a length of 50 mm. The new MFSS composed a neodymium magnet ring, an iron ring, and a magnetic fluid particularly designed for the MFSS. The new MFSS had outer and inner diameters of 4.0 mm and 2.6 mm, respectively, and a length of 3.0 mm. The sealing pressure of the MFSS was calculated to be 432 mmHg using FEM (Finite Element Method) result; therefore, the MFSS had sufficient sealing pressure for the catheter-mounted MFBP. The friction loss of the MFSS included the friction owing to the viscosity of the magnetic fluid and the magnetic force between the iron ring and ring magnet. The total friction loss of the MFSS was 0.08-0.09 W in the pump operational speed range from 22,000 to 35,000 rpm. From the in vitro experimental results, the catheter-mounted MFBP using the MFSS had a pump output of 3 L/min. against a differential pressure of 60 mmHg, and the pump characteristics of the MFBP were almost the same as those of Impella 5.0.In this study, we developed a new catheter-mounted micro-axial flow blood pump (MFBP) using a new miniature magnetic fluid shaft seal (MFSS). The prototype of the catheter-mounted MFBP had a maximum diameter of 8 mm and a length of 50 mm. The new MFSS composed a neodymium magnet ring, an iron ring, and a magnetic fluid particularly designed for the MFSS. The new MFSS had outer and inner diameters of 4.0 mm and 2.6 mm, respectively, and a length of 3.0 mm. The sealing pressure of the MFSS was calculated to be 432 mmHg using FEM (Finite Element Method) result; therefore, the MFSS had sufficient sealing pressure for the catheter-mounted MFBP. The friction loss of the MFSS included the friction owing to the viscosity of the magnetic fluid and the magnetic force between the iron ring and ring magnet. The total friction loss of the MFSS was 0.08-0.09 W in the pump operational speed range from 22,000 to 35,000 rpm. From the in vitro experimental results, the catheter-mounted MFBP using the MFSS had a pump output of 3 L/min. against a differential pressure of 60 mmHg, and the pump characteristics of the MFBP were almost the same as those of Impella 5.0. In this study, we developed a new catheter-mounted micro-axial flow blood pump (MFBP) using a new miniature magnetic fluid shaft seal (MFSS). The prototype of the catheter-mounted MFBP had a maximum diameter of 8 mm and a length of 50 mm. The new MFSS composed a neodymium magnet ring, an iron ring, and a magnetic fluid particularly designed for the MFSS. The new MFSS had outer and inner diameters of 4.0 mm and 2.6 mm, respectively, and a length of 3.0 mm. The sealing pressure of the MFSS was calculated to be 432 mmHg using FEM (Finite Element Method) result; therefore, the MFSS had sufficient sealing pressure for the catheter-mounted MFBP. The friction loss of the MFSS included the friction owing to the viscosity of the magnetic fluid and the magnetic force between the iron ring and ring magnet. The total friction loss of the MFSS was 0.08–0.09 W in the pump operational speed range from 22,000 to 35,000 rpm. From the in vitro experimental results, the catheter-mounted MFBP using the MFSS had a pump output of 3 L/min. against a differential pressure of 60 mmHg, and the pump characteristics of the MFBP were almost the same as those of Impella 5.0. |
Author | Yano, Tetsuya Okamoto, Eiji Sekine, Kazumitsu Inoue, Yusuke Shiraishi, Yasuyuki Yambe, Tomoyuki Mitamura, Yoshinori |
Author_xml | – sequence: 1 givenname: Eiji orcidid: 0000-0003-4382-0343 surname: Okamoto fullname: Okamoto, Eiji email: okamoto29@tsc.u-tokai.ac.jp organization: Graduate School of Biology, Tokai University – sequence: 2 givenname: Tetsuya surname: Yano fullname: Yano, Tetsuya organization: Graduate School of Science and Engineering, Hirosaki University – sequence: 3 givenname: Kazumitsu surname: Sekine fullname: Sekine, Kazumitsu organization: Research Division of Medical & Dental & Pharmacy, Tokushima University – sequence: 4 givenname: Yusuke surname: Inoue fullname: Inoue, Yusuke organization: Advanced Biomedical Research Center, Asahikawa Medical University, Institute of Development Aging and Cancer, Tohoku University – sequence: 5 givenname: Yasuyuki surname: Shiraishi fullname: Shiraishi, Yasuyuki organization: Institute of Development Aging and Cancer, Tohoku University – sequence: 6 givenname: Tomoyuki surname: Yambe fullname: Yambe, Tomoyuki organization: Institute of Development Aging and Cancer, Tohoku University – sequence: 7 givenname: Yoshinori surname: Mitamura fullname: Mitamura, Yoshinori organization: Emeritus Professor, Hokkaido University |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/35426584$$D View this record in MEDLINE/PubMed |
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Cites_doi | 10.1111/j.1525-1594.2009.00899.x 10.4283/JMAG.2017.22.2.286 10.1097/00002480-200107000-00018 10.1097/MAT.0000000000001194 10.1007/s10047-010-0526-8 10.1016/j.jmmm.2016.09.032 10.1016/j.athoracsur.2013.07.053 10.1016/j.carrev.2019.03.010 10.1161/CIRCHEARTFAILURE.112.967224 10.1046/j.1525-1594.2001.025005414.x 10.1016/j.athoracsur.2019.08.041 10.1016/j.jmmm.2019.166293 10.1046/j.1525-1594.2003.00035.x |
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Keywords | Impella Catheter mounted Magnetic fluid shaft seal Axial flow blood pump Magnetic fluid |
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References | Mitamura, Sekine, Okamoto (CR13) 2020; 500 Lemaire, Anderson, Lee, Scholz, Prendergast, Goodman, Lozano, Spotnitz, Batsides (CR5) 2014; 97 Sekine, Mitamura (CR18) 2020; 41 CR4 CR3 Ramzy, Soltesz, Anderson (CR14) 2020; 66 Mitamura, Takahashi, Amari, Okamoto, Murabayashi, Nishimura (CR11) 2011; 14 Sekine, Mitamura, Murabayashi, Nishimura, Yozu, Kim (CR9) 2003; 27 Mitamura, Durst (CR12) 2017; 431 Siess, Nix, Menzler (CR15) 2001; 25 Berkovsky, Medvedev, Krakov (CR16) 1993 Mitamura, Sekine, Asakawa, Yozu, kawada, Okamoto (CR8) 2001; 47 Jianhui, Meng, Lu, Jibin, Li (CR17) 2017; 22 Chung, Emerson, Ramzy, Akhmerov, Megna, Esmailian, Kobashiwaga, Cole, Moriguch, Trento (CR7) 2020; 109 Khalid, Rogers, Shlofmitz, Chen, Musallam, Khan, Iantorno, Gajanana, Hahim, Torguson, Bernardo, Waksman (CR6) 2019; 20 Ramzy, Soltesz, Anderson (CR2) 2020; 66 Mitamura, Takahashi, Kano, Okamoto, Murabayashi, Nishimura, Higuchi (CR10) 2009; 33 Lauten, Engstrom, Jung, Empen, Erne, Cook, Windecker, Bergmann, Klingenberg, Luscher, Haude, Rulands, Butter, Ullman, Hellgren, Modena, Pedrazzini, Henriques, Figulla, Ferrari (CR1) 2013; 6 K Sekine (1330_CR9) 2003; 27 D Ramzy (1330_CR14) 2020; 66 JS Chung (1330_CR7) 2020; 109 Y Mitamura (1330_CR13) 2020; 500 A Lauten (1330_CR1) 2013; 6 1330_CR4 1330_CR3 A Lemaire (1330_CR5) 2014; 97 D Ramzy (1330_CR2) 2020; 66 BM Berkovsky (1330_CR16) 1993 Y Mitamura (1330_CR8) 2001; 47 T Siess (1330_CR15) 2001; 25 Y Mitamura (1330_CR10) 2009; 33 K Sekine (1330_CR18) 2020; 41 Y Mitamura (1330_CR12) 2017; 431 H Jianhui (1330_CR17) 2017; 22 N Khalid (1330_CR6) 2019; 20 Y Mitamura (1330_CR11) 2011; 14 |
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Snippet | In this study, we developed a new catheter-mounted micro-axial flow blood pump (MFBP) using a new miniature magnetic fluid shaft seal (MFSS). The prototype of... |
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SubjectTerms | Axial flow Axial flow pumps Biomedical Engineering and Bioengineering Blood pumps Cardiac Surgery Catheters Differential pressure Finite element method Friction Friction loss Iron Magnetic fields Magnetic fluids Medical instruments Medicine Medicine & Public Health Neodymium Nephrology Original Article Permanent magnets Pressure Sealing |
Title | Development and initial performance of a miniature axial flow blood pump using magnetic fluid shaft seal |
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