The Transient Receptor Potential Channel Yvc1 Deletion Recovers the Growth Defect of Calcineurin Mutant Under Endoplasmic Reticulum Stress in Candida albicans

• Published in: Frontiers in microbiology Vol. 12; p. 752670
• Main Authors: Peng, Liping, Du, Jiawen, Zhang, Runfan, Zhu, Nali, Zhao, He, Zhao, Qiang, Yu, Qilin, Li, Mingchun
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 30.11.2021
• Subjects: calcineurin; calcium transport; Candida albicans; endoplasmic reticulum stress; Microbiology; TRP channel; Candida albicans; TRP channel; calcineurin; calcium transport; endoplasmic reticulum stress

Transient receptor potential (TRP) channel Yvc1 was related with hyphal growth, oxidative stress response, and pathogenicity. Calcineurin subunit Cnb1 was activated immediately in yeasts when exposed to severe stimulation. However, the relationship between Yvc1 and Cnb1-governed calcium ions and end...