Status of Propranolol for Treatment of Infantile Hemangioma and Description of a Randomized Clinical Trial

• Published in: Annals of otology, rhinology & laryngology Vol. 120; no. 10; pp. 686 - 695
• Main Authors: Menezes, Maithilee D., McCarter, Robert, Greene, E. Anne, Bauman, Nancy M.
• Format: Journal Article
• Language: English
• Published: Los Angeles, CA SAGE Publications 01.10.2011; Annals Publishing Compagny; SAGE PUBLICATIONS, INC
• Subjects: Age Factors; Antiarythmic agents; Biological and medical sciences; Cardiovascular system; Child; Child, Preschool; Hemangioma - drug therapy; Humans; Medical sciences; Otorhinolaryngology. Stomatology; Pharmacology. Drug treatments; Prednisolone - therapeutic use; Propranolol - administration & dosage; Propranolol - adverse effects; Propranolol - therapeutic use; Recurrence; Treatment Outcome; hemangioma; acebutolol; review; propranolol; Human; Description; Cardiovascular disease; ENT; Acebutolol; Review; Antiarrhythmic agent; β-Adrenergic receptor; Vascular disease; Angioma; Treatment; Antihypertensive agent; Clinical trial; Antagonist; Propranolol; Child; Bibliographic review; Beta blocking agent

Objectives: Our primary objective was to review the current use of propranolol for treatment of infantile hemangioma (IH), specifically regarding 1) the age at initiation of therapy, 2) the method of initiation, 3) the use of other adjuvant therapy, 4) the duration of therapy and relapse rate, 5) th...