Association of Isocitrate Dehydrogenase (IDH) Status With Edema to Tumor Ratio and Its Correlation With Immune Infiltration in Glioblastoma

• Published in: Frontiers in immunology Vol. 12; p. 627650
• Main Authors: Dubinski, Daniel, Won, Sae-Yeon, Rauch, Maximilian, Behmanesh, Bedjan, Ngassam, Lionel D C, Baumgarten, Peter, Senft, Christian, Harter, Patrick N, Bernstock, Joshua D, Freiman, Thomas M, Seifert, Volker, Gessler, Florian
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 25.03.2021
• Subjects: dexamethasone; glioma microenvironment; immune infiltration; Immunology; peritumoral edema; peritumoral edema zone; dexamethasone; peritumoral edema; peritumoral edema zone; immune infiltration; glioma microenvironment

The extent of preoperative peritumoral edema in glioblastoma (GBM) has been negatively correlated with patient outcome. As several ongoing studies are investigating T-cell based immunotherapy in GBM, we conducted this study to assess whether peritumoral edema with potentially increased intracranial...