GROWTH FACTORS: ROLES IN ANDROLOGY
Mesenchymal-epithelial interactions are extremely important during growth and development and in the functional cytodifferentiation of male sex accessory organs. Interactions between mesenchyme and epithelium occur mainly through a paracrine action that is mediated by various growth factors. The rol...
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Published in | Archives of andrology Vol. 47; no. 1; pp. 1 - 7 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
Philadelphia, PA
Informa UK Ltd
2001
Taylor & Francis |
Subjects | |
Online Access | Get full text |
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Summary: | Mesenchymal-epithelial interactions are extremely important during growth and development and in the functional cytodifferentiation of male sex accessory organs. Interactions between mesenchyme and epithelium occur mainly through a paracrine action that is mediated by various growth factors. The role of androgens is very important for these organs and the androgenic effect is mediated by paracrine interactions. A number of growth factors have been studied in prostate and seminal vesicles from mice, rats, and humans because they are potent mediators of cellular proliferation, differentiation, and death. This review provides an overview of current knowledge about growth factors involved in the development of male sex accessory organs, with particular emphasis on the prostate. |
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Bibliography: | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 |
ISSN: | 0955-3002 0148-5016 1362-3095 1521-0375 |
DOI: | 10.1080/01485010152103946 |