Proteomic and histopathological characterisation of sicca subjects and primary Sjögren’s syndrome patients reveals promising tear, saliva and extracellular vesicle disease biomarkers - Aqrawi, Lara A.; Galtung, Hilde Kanli; Guerreiro, Eduarda M.; Øvstebø, Reidun; Thiede, Bernd; Utheim, Tor Paaske; Chen, Xiangjun; Utheim, Øygunn Aass; Palm, Øyvind; Skarstein, Kathrine; Jensen, Janicke Liaaen (Arthritis research & therapy, 2019)
Keywords: Adult; Aged; Annexin A1 - metabolism; Annexin A5 - metabolism; Autoimmunity; Biomarkers; Biomarkers - metabolism; Biopsy; Extracellular Fluid - metabolism; Female; Humans; Innate immunity; LIM Domain Proteins - metabolism; Male; Mass Spectrometry; Membrane Proteins - metabolism; Middle Aged; Prognosis; Proteomics; Proteomics - methods; Saliva - metabolism; Salivary Glands - pathology; Severity of Illness Index; Sicca subjects; Sjogren's Syndrome - diagnosis; Sjogren's Syndrome - metabolism; Sjögren’s syndrome; Tears - metabolism; Transcription Factors - metabolism; Tumor Suppressor Proteins - metabolism; Ubiquitin-Protein Ligases - metabolism; Autoimmunity; Sicca subjects; Proteomics; Biomarkers; Extracellular vesicles; Innate immunity; Sjögren’s syndrome; Adaptive immunity; Saliva; Tears