Acute Cold Water-Immersion Restraint Stress Induces Intestinal Injury and Reduces the Diversity of Gut Microbiota in Mice

• Published in: Frontiers in cellular and infection microbiology Vol. 11; p. 706849
• Main Authors: Zhang, Yuan, Wu, Shuwen, Liu, Yongming, Ma, Jingchang, Li, Wenpeng, Xu, Xuexue, Wang, Yuling, Luo, Yanling, Cheng, Kun, Zhuang, Ran
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 14.10.2021
• Subjects: Animals; Cellular and Infection Microbiology; cold water-immersion restraint stress; Cold-Shock Response; Gastrointestinal Microbiome; gut microbiota; Immersion; inflammation; intestinal injury; Intestinal Mucosa; Male; Mice; Mice, Inbred C57BL; mouse models; RNA, Ribosomal, 16S - genetics; Water; cold water-immersion restraint stress; mouse models; inflammation; gut microbiota; intestinal injury

Growing evidence has demonstrated that stress triggers gastrointestinal (GI) disorders. This study aimed to investigate how the acute cold water-immersion restraint (CWIR) stress affects intestinal injury and gut microbiota (GM) distribution. Male C57BL/6 mice were used to establish a CWIR animal mo...