B7-H3/CD276: An Emerging Cancer Immunotherapy

• Published in: Frontiers in immunology Vol. 12; p. 701006
• Main Authors: Zhou, Wu-Tong, Jin, Wei-Lin
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 19.07.2021
• Subjects: Animals; B7 Antigens; B7-H3/CD276; cancer immunotherapy; Humans; immune checkpoint; Immunology; Immunotherapy - methods; Neoplasms; tumor immunology; Tumor Microenvironment; tumor immunology; tumor microenvironment; B7-H3/CD276; cancer immunotherapy; immune checkpoint

Immunotherapy aiming at suppressing tumor development by relying on modifying or strengthening the immune system prevails among cancer treatments and points out a new direction for cancer therapy. B7 homolog 3 protein (B7-H3, also known as CD276), a newly identified immunoregulatory protein member o...