Gut Microbiota and Diarrhea: An Updated Review

Diarrhea is a common problem to the whole world and the occurrence of diarrhea is highly associated with gut microbiota, such as bacteria, fungi, and viruses. Generally, diarrheal patients or animals are characterized by gut microbiota dysbiosis and pathogen infections may lead to diarrheal phenotyp...

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Published inFrontiers in cellular and infection microbiology Vol. 11; p. 625210
Main Authors Li, Yunxia, Xia, Siting, Jiang, Xiaohan, Feng, Can, Gong, Saiming, Ma, Jie, Fang, Zhengfeng, Yin, Jie, Yin, Yulong
Format Journal Article
LanguageEnglish
Published Switzerland Frontiers Media S.A 15.04.2021
Subjects
Cellular and Infection Microbiology
diarrhea
fecal microbiota transplantation
gut microbiota
intestinal health
probiotics
intestinal health
diarrhea
fecal microbiota transplantation
gut microbiota
probiotics
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Abstract Diarrhea is a common problem to the whole world and the occurrence of diarrhea is highly associated with gut microbiota, such as bacteria, fungi, and viruses. Generally, diarrheal patients or animals are characterized by gut microbiota dysbiosis and pathogen infections may lead to diarrheal phenotypes. Of relevance, reprograming gut microbiota communities by dietary probiotics or fecal bacteria transplantation are widely introduced to treat or prevent diarrhea. In this review, we discussed the influence of the gut microbiota in the infection of diarrhea pathogens, and updated the research of reshaping the gut microbiota to prevent or treat diarrhea for the past few years. Together, gut microbiota manipulation is of great significance to the prevention and treatment of diarrhea, and further insight into the function of the gut microbiota will help to discover more anti-diarrhea probiotics.
AbstractList Diarrhea is a common problem to the whole world and the occurrence of diarrhea is highly associated with gut microbiota, such as bacteria, fungi, and viruses. Generally, diarrheal patients or animals are characterized by gut microbiota dysbiosis and pathogen infections may lead to diarrheal phenotypes. Of relevance, reprograming gut microbiota communities by dietary probiotics or fecal bacteria transplantation are widely introduced to treat or prevent diarrhea. In this review, we discussed the influence of the gut microbiota in the infection of diarrhea pathogens, and updated the research of reshaping the gut microbiota to prevent or treat diarrhea for the past few years. Together, gut microbiota manipulation is of great significance to the prevention and treatment of diarrhea, and further insight into the function of the gut microbiota will help to discover more anti-diarrhea probiotics.
Author Li, Yunxia
Yin, Jie
Gong, Saiming
Jiang, Xiaohan
Fang, Zhengfeng
Feng, Can
Yin, Yulong
Xia, Siting
Ma, Jie
AuthorAffiliation 3 Institute of Subtropical Agriculture, Chinese Academy of Sciences , Changsha , China
1 Animal Nutritional Genome and Germplasm Innovation Research Center, College of Animal Science and Technology, Hunan Agricultural University , Changsha , China
2 Animal Nutrition Institute, Sichuan Agricultural University , Chengdu , China
AuthorAffiliation_xml – name: 2 Animal Nutrition Institute, Sichuan Agricultural University , Chengdu , China
– name: 3 Institute of Subtropical Agriculture, Chinese Academy of Sciences , Changsha , China
– name: 1 Animal Nutritional Genome and Germplasm Innovation Research Center, College of Animal Science and Technology, Hunan Agricultural University , Changsha , China
Author_xml – sequence: 1
  givenname: Yunxia
  surname: Li
  fullname: Li, Yunxia
  organization: Animal Nutritional Genome and Germplasm Innovation Research Center, College of Animal Science and Technology, Hunan Agricultural University, Changsha, China
– sequence: 2
  givenname: Siting
  surname: Xia
  fullname: Xia, Siting
  organization: Animal Nutritional Genome and Germplasm Innovation Research Center, College of Animal Science and Technology, Hunan Agricultural University, Changsha, China
– sequence: 3
  givenname: Xiaohan
  surname: Jiang
  fullname: Jiang, Xiaohan
  organization: Animal Nutritional Genome and Germplasm Innovation Research Center, College of Animal Science and Technology, Hunan Agricultural University, Changsha, China
– sequence: 4
  givenname: Can
  surname: Feng
  fullname: Feng, Can
  organization: Animal Nutritional Genome and Germplasm Innovation Research Center, College of Animal Science and Technology, Hunan Agricultural University, Changsha, China
– sequence: 5
  givenname: Saiming
  surname: Gong
  fullname: Gong, Saiming
  organization: Animal Nutritional Genome and Germplasm Innovation Research Center, College of Animal Science and Technology, Hunan Agricultural University, Changsha, China
– sequence: 6
  givenname: Jie
  surname: Ma
  fullname: Ma, Jie
  organization: Animal Nutritional Genome and Germplasm Innovation Research Center, College of Animal Science and Technology, Hunan Agricultural University, Changsha, China
– sequence: 7
  givenname: Zhengfeng
  surname: Fang
  fullname: Fang, Zhengfeng
  organization: Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, China
– sequence: 8
  givenname: Jie
  surname: Yin
  fullname: Yin, Jie
  organization: Animal Nutritional Genome and Germplasm Innovation Research Center, College of Animal Science and Technology, Hunan Agricultural University, Changsha, China
– sequence: 9
  givenname: Yulong
  surname: Yin
  fullname: Yin, Yulong
  organization: Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, China
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ContentType Journal Article
Copyright Copyright © 2021 Li, Xia, Jiang, Feng, Gong, Ma, Fang, Yin and Yin.
Copyright © 2021 Li, Xia, Jiang, Feng, Gong, Ma, Fang, Yin and Yin 2021 Li, Xia, Jiang, Feng, Gong, Ma, Fang, Yin and Yin
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Keywords intestinal health
diarrhea
fecal microbiota transplantation
gut microbiota
probiotics
Language English
License Copyright © 2021 Li, Xia, Jiang, Feng, Gong, Ma, Fang, Yin and Yin.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
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Reviewed by: Thibault Géry Sana, Le nouvel Institut national de recherche sur l'agriculture, l’alimentation et l’environnement en France INRAE, France; Yuehe Ding, University of Massachusetts Medical School, United States
This article was submitted to Microbiome in Health and Disease, a section of the journal Frontiers in Cellular and Infection Microbiology
Edited by: Qiyuan Yang, University of Massachusetts Medical School, United States
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SubjectTerms Cellular and Infection Microbiology
diarrhea
fecal microbiota transplantation
gut microbiota
intestinal health
probiotics
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Title Gut Microbiota and Diarrhea: An Updated Review
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