Gut Microbiota and Diarrhea: An Updated Review

Diarrhea is a common problem to the whole world and the occurrence of diarrhea is highly associated with gut microbiota, such as bacteria, fungi, and viruses. Generally, diarrheal patients or animals are characterized by gut microbiota dysbiosis and pathogen infections may lead to diarrheal phenotyp...

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Published inFrontiers in cellular and infection microbiology Vol. 11; p. 625210
Main Authors Li, Yunxia, Xia, Siting, Jiang, Xiaohan, Feng, Can, Gong, Saiming, Ma, Jie, Fang, Zhengfeng, Yin, Jie, Yin, Yulong
Format Journal Article
LanguageEnglish
Published Switzerland Frontiers Media S.A 15.04.2021
Subjects
Cellular and Infection Microbiology
diarrhea
fecal microbiota transplantation
gut microbiota
intestinal health
probiotics
intestinal health
diarrhea
fecal microbiota transplantation
gut microbiota
probiotics
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Abstract Diarrhea is a common problem to the whole world and the occurrence of diarrhea is highly associated with gut microbiota, such as bacteria, fungi, and viruses. Generally, diarrheal patients or animals are characterized by gut microbiota dysbiosis and pathogen infections may lead to diarrheal phenotypes. Of relevance, reprograming gut microbiota communities by dietary probiotics or fecal bacteria transplantation are widely introduced to treat or prevent diarrhea. In this review, we discussed the influence of the gut microbiota in the infection of diarrhea pathogens, and updated the research of reshaping the gut microbiota to prevent or treat diarrhea for the past few years. Together, gut microbiota manipulation is of great significance to the prevention and treatment of diarrhea, and further insight into the function of the gut microbiota will help to discover more anti-diarrhea probiotics.
AbstractList Diarrhea is a common problem to the whole world and the occurrence of diarrhea is highly associated with gut microbiota, such as bacteria, fungi, and viruses. Generally, diarrheal patients or animals are characterized by gut microbiota dysbiosis and pathogen infections may lead to diarrheal phenotypes. Of relevance, reprograming gut microbiota communities by dietary probiotics or fecal bacteria transplantation are widely introduced to treat or prevent diarrhea. In this review, we discussed the influence of the gut microbiota in the infection of diarrhea pathogens, and updated the research of reshaping the gut microbiota to prevent or treat diarrhea for the past few years. Together, gut microbiota manipulation is of great significance to the prevention and treatment of diarrhea, and further insight into the function of the gut microbiota will help to discover more anti-diarrhea probiotics.
Diarrhea is a common problem to the whole world and the occurrence of diarrhea is highly associated with gut microbiota, such as bacteria, fungi, and viruses. Generally, diarrheal patients or animals are characterized by gut microbiota dysbiosis and pathogen infections may lead to diarrheal phenotypes. Of relevance, reprograming gut microbiota communities by dietary probiotics or fecal bacteria transplantation are widely introduced to treat or prevent diarrhea. In this review, we discussed the influence of the gut microbiota in the infection of diarrhea pathogens, and updated the research of reshaping the gut microbiota to prevent or treat diarrhea for the past few years. Together, gut microbiota manipulation is of great significance to the prevention and treatment of diarrhea, and further insight into the function of the gut microbiota will help to discover more anti-diarrhea probiotics.Diarrhea is a common problem to the whole world and the occurrence of diarrhea is highly associated with gut microbiota, such as bacteria, fungi, and viruses. Generally, diarrheal patients or animals are characterized by gut microbiota dysbiosis and pathogen infections may lead to diarrheal phenotypes. Of relevance, reprograming gut microbiota communities by dietary probiotics or fecal bacteria transplantation are widely introduced to treat or prevent diarrhea. In this review, we discussed the influence of the gut microbiota in the infection of diarrhea pathogens, and updated the research of reshaping the gut microbiota to prevent or treat diarrhea for the past few years. Together, gut microbiota manipulation is of great significance to the prevention and treatment of diarrhea, and further insight into the function of the gut microbiota will help to discover more anti-diarrhea probiotics.
Author Li, Yunxia
Yin, Jie
Gong, Saiming
Jiang, Xiaohan
Fang, Zhengfeng
Feng, Can
Yin, Yulong
Xia, Siting
Ma, Jie
AuthorAffiliation 3 Institute of Subtropical Agriculture, Chinese Academy of Sciences , Changsha , China
1 Animal Nutritional Genome and Germplasm Innovation Research Center, College of Animal Science and Technology, Hunan Agricultural University , Changsha , China
2 Animal Nutrition Institute, Sichuan Agricultural University , Chengdu , China
AuthorAffiliation_xml – name: 2 Animal Nutrition Institute, Sichuan Agricultural University , Chengdu , China
– name: 3 Institute of Subtropical Agriculture, Chinese Academy of Sciences , Changsha , China
– name: 1 Animal Nutritional Genome and Germplasm Innovation Research Center, College of Animal Science and Technology, Hunan Agricultural University , Changsha , China
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  givenname: Yunxia
  surname: Li
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– sequence: 2
  givenname: Siting
  surname: Xia
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– sequence: 3
  givenname: Xiaohan
  surname: Jiang
  fullname: Jiang, Xiaohan
– sequence: 4
  givenname: Can
  surname: Feng
  fullname: Feng, Can
– sequence: 5
  givenname: Saiming
  surname: Gong
  fullname: Gong, Saiming
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  surname: Ma
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  fullname: Yin, Jie
– sequence: 9
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Cites_doi 10.1080/21553769.2015.1051243
10.1038/s41598-018-23404-4
10.1039/c8fo00376a
10.3920/BM2016.0157
10.3390/toxins13010012
10.1073/pnas.1915255117
10.1016/j.chom.2018.11.006
10.1038/s41598-020-60792-y
10.3389/fmicb.2017.01798
10.1038/nrdp.2017.83
10.3920/BM2018.0066
10.4014/jmb.2002.02044
10.1128/JCM.01810-15
10.3390/microorganisms7020051
10.1128/JVI.75.3.1540-1546.2001
10.1038/s41426-017-0019-4
10.4161/gmic.1.1.11036
10.7189/jogh.09.020801
10.1128/mBio.01183-14
10.1128/mSystems.00346-18
10.3748/wjg.v22.i32.7186
10.1128/JVI.78.19.10213-10220.2004
10.4315/0362-028x-73.3.452
10.1128/mSystems.00002-20
10.1038/nature07067
10.1264/jsme2.ME17017
10.1038/sj.emboj.7600594
10.1093/jpids/piw020
10.3389/fcimb.2020.572096
10.1371/journal.pone.0012164
10.1093/jtm/taw086
10.2527/jas.2013-6528
10.1080/19490976.2017.1293224
10.3855/jidc.9538
10.1016/j.micpath.2018.02.032
10.1056/NEJMoa051590
10.3748/wjg.v23.i42.7584
10.1128/CMR.00006-15
10.1016/j.cell.2015.11.032
10.1371/journal.ppat.1002933
10.3748/wjg.v25.i33.4999
10.1128/IAI.00246-20
10.1007/978-1-4614-4726-9_5
10.1111/1462-2920.15040
10.1128/iai.72.4.2240-2247.2004
10.1152/ajpgi.1999.277.2.G431
10.1016/j.tim.2017.05.004
10.1128/mSystems.00137-18
10.1017/S0007114516004037
10.1016/j.tim.2019.05.002
10.1093/ibd/izz299
10.1016/S2214-109X(19)30541-8
10.1111/hel.12237
10.1097/QCO.0000000000000475
10.1128/JCM.03058-14
10.1007/s11892-019-1180-z
10.1016/j.bjm.2016.10.015
10.1016/S2468-1253(17)30147-4
10.1126/science.272.5258.101
10.1093/infdis/155.3.377
10.3389/fmicb.2016.00789
10.1001/jama.2018.20046
10.3389/fimmu.2015.00612
10.1016/S1473-3099(17)30276-1
10.3390/cells8060517
10.3748/wjg.v21.i29.8787
10.1038/ajg.2014.427
10.1007/s00253-019-09978-7
10.1038/nrgastro.2017.75
10.1080/19490976.2019.1662712
10.4314/ahs.v17i2.5
10.1136/gutjnl-2018-316434
10.1016/j.tim.2020.06.009
10.1128/CMR.00002-15
10.1099/0022-1317-51-3-201
10.1038/ajg.2010.11
10.1007/s13205-017-0953-9
10.1016/j.celrep.2016.03.015
10.1111/cmi.13062
10.1146/annurev-micro-091014-104330
10.1016/j.beem.2021.101507
10.12659/MSM.920879
10.1016/j.aninu.2020.08.001
10.1038/s41579-020-0433-9
10.1017/S0007114516004566
10.3389/fimmu.2018.01318
10.3390/nu12020498
10.1038/nature18846
10.1038/s41598-020-69533-7
10.1016/j.cppeds.2020.100841
10.1111/j.1600-065X.2011.01070.x
10.1016/s0889-8553(05)70210-7
10.1126/science.1222195
10.1038/s41598-019-40859-1
10.1053/j.gastro.2016.11.010
10.1111/imcb.12409
10.1097/INF.0000000000001232
10.1016/S2468-1253(17)30338-2
10.1053/j.gastro.2016.10.014
10.1007/s12223-020-00773-w
10.1007/s10096-019-03539-6
10.1007/BF00632335
10.1097/00005176-200110002-00004
ContentType Journal Article
Copyright Copyright © 2021 Li, Xia, Jiang, Feng, Gong, Ma, Fang, Yin and Yin.
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Keywords intestinal health
diarrhea
fecal microbiota transplantation
gut microbiota
probiotics
Language English
License Copyright © 2021 Li, Xia, Jiang, Feng, Gong, Ma, Fang, Yin and Yin.
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Reviewed by: Thibault Géry Sana, Le nouvel Institut national de recherche sur l'agriculture, l’alimentation et l’environnement en France INRAE, France; Yuehe Ding, University of Massachusetts Medical School, United States
This article was submitted to Microbiome in Health and Disease, a section of the journal Frontiers in Cellular and Infection Microbiology
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References Cheng (B17) 2018; 3
Wen (B99) 2019; 7
Kaiser (B50) 2012; 245
Snelson (B88) 2021; 17
Burrello (B15) 2019; 8
De Jong (B25) 2012; 8
Tariq (B93) 2020; 26
Yin (B101) 2020; 5
Lamberti (B54) 2016; 35
Antunes (B3) 2014; 5
Li (B58) 2019; 25
Nobile (B69) 2015; 69
Sangster (B85) 2016; 7
Mileto (B63) 2020; 117
Rigo-Adrover (B82) 2017; 117
Zeng (B102) 2017; 8
Jiang (B47) 2017; 8
Johnsen (B48) 2018; 3
Paparo (B73) 2020; 10
Ramig (B81) 2004; 78
Aron-Wisnewsky (B4) 2019; 19
Ball (B10) 1996; 272
Asahara (B5) 2004; 72
Bayoumi (B11) 2010; 73
Czepiel (B22) 2019; 38
Emara (B28) 2016; 21
Crawford (B20) 2017; 3
Costello (B19) 2019; 321
Quesada-Gómez (B78) 2015; 53
Monteagudo-Mera (B65) 2019; 103
Azagra-Boronat (B8) 2020; 12
Levine (B55) 2020; 8
Androga (B2) 2015; 53
Ramamurthy (B80) 2020; 10
Gorelik (B38) 2019; 9
Hodges (B44) 2010; 1
Knodler (B53) 2019; 27
Halkjaer (B40) 2018; 67
Do Carmo (B27) 2018; 9
Szajewska (B91) 2001; 33
McKenney (B62) 2015; 163
Eng (B29) 2015; 8
Hillman (B42) 2017; 32
Rigo-Adrover (B83) 2018; 9
Vezzulli (B96) 2020; 22
Vogt (B97) 2017; 24
Long (B60) 2017; 23
Camilleri (B16) 2017; 152
Kaakoush (B49) 2015; 28
Morris (B66) 1999; 277
Hu (B45) 2018; 24
Zhang (B103) 2020; 30
Panpetch (B72) 2020; 11
Kawashima (B52) 2018; 8
Ward (B98) 2016; 14
Gantner (B32) 2005; 24
Mirhoseini (B64) 2018; 117
Chu (B18) 2020; 50
Gresse (B39) 2017; 25
Peng (B74) 2018; 7
Awoyeni (B6) 2017; 17
Crump (B21) 2015; 28
Baker (B9) 2018; 31
Troeger (B95) 2017; 17
Peters (B75) 2019; 10
Gallo (B31) 2016; 22
Nataro (B67) 2013; 764
Ackermann (B1) 2008; 454
Liu (B57) 2019; 21
Sonnenburg (B89) 2016; 535
Levine (B56) 1987; 155
De Groot (B24) 2017; 8
Sazawal (B86) 2010; 5
Shin (B87) 2002; 51
Ogura (B70) 2020; 13
Wu (B100) 2020; 26
De Santis (B26) 2015; 7
Ott (B71) 2017; 152
Hirayama (B43) 2020; 10
Bron (B13) 2017; 117
Goodgame (B37) 2001; 30
Rajilić-Stojanović (B79) 2015; 110
Gibson (B35) 2017; 14
Gomes (B36) 2016; 47
Black (B12) 2019; 9
Liu (B59) 2020; 88
Torres-Fuentes (B94) 2017; 2
Ryan (B84) 2020
Azad (B7) 2020; 6
He (B41) 2017; 7
Fan (B30) 2020; 19
Gao (B34) 2013; 91
Broujerdi (B14) 2018; 12
McDonald (B61) 2005; 353
Pujari (B77) 2021; 99
Kamada (B51) 2012; 336
Nisa (B68) 2020; 65
Gao (B33) 2010; 105
Ponnuvel (B76) 1996; 135
Jandhyala (B46) 2015; 21
Tafazoli (B92) 2001; 75
Stockmann (B90) 2017; 6
Darkoh (B23) 2019; 4
References_xml – volume: 8
  start-page: 1
  year: 2015
  ident: B29
  article-title: Salmonella: A review on pathogenesis, epidemiology and antibiotic resistance
  publication-title: Front. Life Sci.
  doi: 10.1080/21553769.2015.1051243
– volume: 8
  start-page: 1
  year: 2018
  ident: B52
  article-title: The molecular mechanism for activating IgA production by Pediococcus acidilactici K15 and the clinical impact in a randomized trial
  publication-title: Sci. Rep.
  doi: 10.1038/s41598-018-23404-4
– volume: 9
  start-page: 5074
  year: 2018
  ident: B27
  article-title: Probiotics, mechanisms of action, and clinical perspectives for diarrhea management in children
  publication-title: Food Funct.
  doi: 10.1039/c8fo00376a
– volume: 8
  start-page: 645
  year: 2017
  ident: B47
  article-title: Effects of Lactobacillus rhamnosus GG on the maturation and differentiation of dendritic cells in rotavirus-infected mice
  publication-title: Benef. Microbes
  doi: 10.3920/BM2016.0157
– volume: 13
  year: 2020
  ident: B70
  article-title: Cell Death Signaling Pathway Induced by Cholix Toxin, a Cytotoxin and eEF2 ADP-Ribosyltransferase Produced by Vibrio cholerae
  publication-title: Toxins
  doi: 10.3390/toxins13010012
– volume: 117
  start-page: 8064
  year: 2020
  ident: B63
  article-title: Clostridioides difficile infection damages colonic stem cells via TcdB, impairing epithelial repair and recovery from disease
  publication-title: P Natl. Acad. Sci. U.S.A.
  doi: 10.1073/pnas.1915255117
– volume: 24
  start-page: 817
  year: 2018
  ident: B45
  article-title: A Microbiota-Derived Bacteriocin Targets the Host to Confer Diarrhea Resistance in Early-Weaned Piglets
  publication-title: Cell Host Microbe
  doi: 10.1016/j.chom.2018.11.006
– volume: 10
  start-page: 1
  year: 2020
  ident: B43
  article-title: Virulence assessment of six major pathogenic Candida species in the mouse model of invasive candidiasis caused by fungal translocation
  publication-title: Sci. Rep.-UK
  doi: 10.1038/s41598-020-60792-y
– volume: 8
  year: 2017
  ident: B102
  article-title: Probiotic Mixture Golden Bifido Prevents Neonatal Escherichia coli K1 Translocation via Enhancing Intestinal Defense
  publication-title: Front. Microbiol.
  doi: 10.3389/fmicb.2017.01798
– volume: 3
  start-page: 1
  year: 2017
  ident: B20
  article-title: Rotavirus infection
  publication-title: Nat. Rev. Dis. Primers.
  doi: 10.1038/nrdp.2017.83
– volume: 10
  start-page: 225
  year: 2019
  ident: B75
  article-title: Mechanisms and immunomodulatory properties of pre- and probiotics
  publication-title: Benef. Microbes
  doi: 10.3920/BM2018.0066
– volume: 30
  start-page: 1132
  year: 2020
  ident: B103
  article-title: Fecal Microbiota Transplantation (FMT) Alleviates Experimental Colitis in Mice by Gut Microbiota Regulation
  publication-title: J. Microbiol. Biotechnol.
  doi: 10.4014/jmb.2002.02044
– volume: 53
  start-page: 3702
  year: 2015
  ident: B2
  article-title: Infection with Toxin A-Negative, Toxin B-Negative, Binary Toxin-Positive Clostridium difficile in a Young Patient with Ulcerative Colitis
  publication-title: J. Clin. Microbiol.
  doi: 10.1128/JCM.01810-15
– volume: 7
  year: 2019
  ident: B99
  article-title: Effects of Bifidobacterium bifidum in Mice Infected with Citrobacter rodentium
  publication-title: Microorganisms
  doi: 10.3390/microorganisms7020051
– volume: 75
  start-page: 1540
  year: 2001
  ident: B92
  article-title: NSP4 enterotoxin of rotavirus induces paracellular leakage in polarized epithelial cells
  publication-title: J. Virol.
  doi: 10.1128/JVI.75.3.1540-1546.2001
– volume: 7
  start-page: 1
  year: 2018
  ident: B74
  article-title: Advances in the diagnosis and treatment of Clostridium difficile infections
  publication-title: Emerg. Microbes Infect.
  doi: 10.1038/s41426-017-0019-4
– volume: 1
  start-page: 4
  year: 2010
  ident: B44
  article-title: Infectious diarrhea
  publication-title: Gut Microbes
  doi: 10.4161/gmic.1.1.11036
– volume: 9
  year: 2019
  ident: B12
  article-title: Drivers of the reduction in childhood diarrhea mortality 1980-2015 and interventions to eliminate preventable diarrhea deaths by 2030
  publication-title: J. Glob. Health
  doi: 10.7189/jogh.09.020801
– volume: 5
  start-page: e01183
  year: 2014
  ident: B3
  article-title: Antivirulence activity of the human gut metabolome
  publication-title: MBio
  doi: 10.1128/mBio.01183-14
– volume: 4
  start-page: e00346
  year: 2019
  ident: B23
  article-title: Clostridium difficile Modulates the Gut Microbiota by Inducing the Production of Indole, an Interkingdom Signaling and Antimicrobial Molecule
  publication-title: Msystems
  doi: 10.1128/mSystems.00346-18
– volume: 22
  start-page: 7186
  year: 2016
  ident: B31
  article-title: Modulation of microbiota as treatment for intestinal inflammatory disorders: An uptodate
  publication-title: World J. Gastroenterol.
  doi: 10.3748/wjg.v22.i32.7186
– volume: 78
  start-page: 10213
  year: 2004
  ident: B81
  article-title: Pathogenesis of intestinal and systemic rotavirus infection
  publication-title: J. Virol.
  doi: 10.1128/JVI.78.19.10213-10220.2004
– volume: 73
  start-page: 452
  year: 2010
  ident: B11
  article-title: Probiotics down-regulate genes in Salmonella enterica serovar typhimurium pathogenicity islands 1 and 2
  publication-title: J. Food Protect.
  doi: 10.4315/0362-028x-73.3.452
– volume: 5
  start-page: e00002
  year: 2020
  ident: B101
  article-title: Administration of Exogenous Melatonin Improves the Diurnal Rhythms of the Gut Microbiota in Mice Fed a High-Fat Diet
  publication-title: mSystems
  doi: 10.1128/mSystems.00002-20
– volume: 454
  start-page: 987
  year: 2008
  ident: B1
  article-title: Self-destructive cooperation mediated by phenotypic noise
  publication-title: Nature
  doi: 10.1038/nature07067
– volume: 32
  start-page: 300
  year: 2017
  ident: B42
  article-title: Microbial Ecology along the Gastrointestinal Tract
  publication-title: Microbes Environ.
  doi: 10.1264/jsme2.ME17017
– volume: 24
  start-page: 1277
  year: 2005
  ident: B32
  article-title: Dectin-1 mediates macrophage recognition of Candida albicans yeast but not filaments
  publication-title: EMBO J.
  doi: 10.1038/sj.emboj.7600594
– volume: 6
  start-page: 231
  year: 2017
  ident: B90
  article-title: Detection of 23 Gastrointestinal Pathogens Among Children Who Present With Diarrhea
  publication-title: J. Pediat. Inf. Dis. Soc.
  doi: 10.1093/jpids/piw020
– volume: 10
  year: 2020
  ident: B80
  article-title: Virulence Regulation and Innate Host Response in the Pathogenicity of Vibrio cholerae
  publication-title: Front. Cell Infect. Mi.
  doi: 10.3389/fcimb.2020.572096
– volume: 5
  start-page: e12164
  year: 2010
  ident: B86
  article-title: Prebiotic and probiotic fortified milk in prevention of morbidities among children: community-based, randomized, double-blind, controlled trial
  publication-title: PloS One
  doi: 10.1371/journal.pone.0012164
– volume: 24
  start-page: S39
  year: 2017
  ident: B97
  article-title: Gut microbiota-mediated protection against diarrheal infections
  publication-title: J. Travel Med.
  doi: 10.1093/jtm/taw086
– volume: 91
  start-page: 5614
  year: 2013
  ident: B34
  article-title: Changes in gut microbial populations, intestinal morphology, expression of tight junction proteins, and cytokine production between two pig breeds after challenge with Escherichia coli K88: a comparative study
  publication-title: J. Anim. Sci.
  doi: 10.2527/jas.2013-6528
– volume: 8
  start-page: 253
  year: 2017
  ident: B24
  article-title: Fecal microbiota transplantation in metabolic syndrome: History, present and future
  publication-title: Gut Microbes
  doi: 10.1080/19490976.2017.1293224
– volume: 12
  start-page: 649
  year: 2018
  ident: B14
  article-title: Characterization of diarrheagenic escherichia coli strains associated with diarrhea in children, khouzestan, iran
  publication-title: J. Infect. Dev. Countr
  doi: 10.3855/jidc.9538
– volume: 117
  start-page: 162
  year: 2018
  ident: B64
  article-title: Review on pathogenicity mechanism of enterotoxigenic Escherichia coli and vaccines against it
  publication-title: Microb. Pathogen.
  doi: 10.1016/j.micpath.2018.02.032
– volume: 353
  start-page: 2433
  year: 2005
  ident: B61
  article-title: An epidemic, toxin gene-variant strain of Clostridium difficile
  publication-title: New Engl. J. Med.
  doi: 10.1056/NEJMoa051590
– volume: 23
  year: 2017
  ident: B60
  article-title: Diversity of bacterial lactase genes in intestinal contents of mice with antibiotics-induced diarrhea
  publication-title: World J. Gastroenterol.
  doi: 10.3748/wjg.v23.i42.7584
– volume: 28
  start-page: 687
  year: 2015
  ident: B49
  article-title: Global Epidemiology of Campylobacter Infection
  publication-title: Clin. Microbiol. Rev.
  doi: 10.1128/CMR.00006-15
– volume: 163
  start-page: 1326
  year: 2015
  ident: B62
  article-title: From Hype to Hope: The Gut Microbiota in Enteric Infectious Disease
  publication-title: Cell
  doi: 10.1016/j.cell.2015.11.032
– volume: 8
  start-page: e1002933
  year: 2012
  ident: B25
  article-title: Host-pathogen interaction in invasive Salmonellosis
  publication-title: PloS Pathog.
  doi: 10.1371/journal.ppat.1002933
– volume: 25
  start-page: 4999
  year: 2019
  ident: B58
  article-title: Efficacy of Lactobacillus rhamnosus GG in treatment of acute pediatric diarrhea: A systematic review with meta-analysis
  publication-title: World J. Gastroenterol.
  doi: 10.3748/wjg.v25.i33.4999
– volume: 88
  start-page: e00246
  year: 2020
  ident: B59
  article-title: Cross-Reactivity, Epitope Mapping, and Potency of Monoclonal Antibodies to Class 5 Fimbrial Tip Adhesins of Enterotoxigenic Escherichia coli
  publication-title: Infect. Immun.
  doi: 10.1128/IAI.00246-20
– volume: 764
  start-page: 73
  year: 2013
  ident: B67
  article-title: Diarrhea among children in developing countries
  publication-title: Adv. Exp. Med. Biol.
  doi: 10.1007/978-1-4614-4726-9_5
– volume: 22
  start-page: 4342
  year: 2020
  ident: B96
  article-title: Global emergence of environmental non-O1/O139 Vibrio cholerae infections linked with climate change: a neglected research field
  publication-title: Environ. Microbiol.
  doi: 10.1111/1462-2920.15040
– volume: 72
  start-page: 2240
  year: 2004
  ident: B5
  article-title: Probiotic bifidobacteria protect mice from lethal infection with Shiga toxin-producing Escherichia coli O157:H7
  publication-title: Infect. Immun.
  doi: 10.1128/iai.72.4.2240-2247.2004
– volume: 277
  start-page: 431
  year: 1999
  ident: B66
  article-title: NSP4 elicits age-dependent diarrhea and Ca(2+)mediated I(-) influx into intestinal crypts of CF mice
  publication-title: Am. J. Physiol.
  doi: 10.1152/ajpgi.1999.277.2.G431
– volume: 25
  start-page: 851
  year: 2017
  ident: B39
  article-title: Gut Microbiota Dysbiosis in Postweaning Piglets: Understanding the Keys to Health
  publication-title: Trends Microbiol.
  doi: 10.1016/j.tim.2017.05.004
– volume: 3
  start-page: e00137
  year: 2018
  ident: B17
  article-title: Fecal Microbiota Transplantation Beneficially Regulates Intestinal Mucosal Autophagy and Alleviates Gut Barrier Injury
  publication-title: Msystems
  doi: 10.1128/mSystems.00137-18
– volume: 117
  start-page: 93
  year: 2017
  ident: B13
  article-title: Can probiotics modulate human disease by impacting intestinal barrier function
  publication-title: Brit. J. Nutr.
  doi: 10.1017/S0007114516004037
– volume: 27
  start-page: 964
  year: 2019
  ident: B53
  article-title: Salmonella enterica
  publication-title: Trends Microbiol
  doi: 10.1016/j.tim.2019.05.002
– volume: 26
  start-page: 1415
  year: 2020
  ident: B93
  article-title: Efficacy of Fecal Microbiota Transplantation for Recurrent C. Difficile Infection in Inflammatory Bowel Disease
  publication-title: Inflammation Bowel. Dis.
  doi: 10.1093/ibd/izz299
– volume: 8
  start-page: e204
  year: 2020
  ident: B55
  article-title: Diarrhoeal disease and subsequent risk of death in infants and children residing in low-income and middle-income countries: analysis of the GEMS case-control study and 12-month GEMS-1A follow-on study
  publication-title: Lancet Glob. Health
  doi: 10.1016/S2214-109X(19)30541-8
– volume: 21
  start-page: 3
  year: 2016
  ident: B28
  article-title: Emerging Role of Probiotics in the Management of Helicobacter pylori Infection: Histopathologic Perspectives
  publication-title: Helicobacter.
  doi: 10.1111/hel.12237
– volume: 31
  start-page: 449
  year: 2018
  ident: B9
  article-title: Recent insights into Shigella: a major contributor to the global diarrhoeal disease burden
  publication-title: Curr. Opin. Infect. Dis.
  doi: 10.1097/QCO.0000000000000475
– volume: 53
  start-page: 1216
  year: 2015
  ident: B78
  article-title: Emergence of an outbreak-associated Clostridium difficile variant with increased virulence
  publication-title: J. Clin. Microbiol.
  doi: 10.1128/JCM.03058-14
– volume: 19
  start-page: 51
  year: 2019
  ident: B4
  article-title: Fecal Microbiota Transplantation: a Future Therapeutic Option for Obesity/Diabetes
  publication-title: Curr. Diabetes Rep.
  doi: 10.1007/s11892-019-1180-z
– volume: 47
  start-page: 3
  year: 2016
  ident: B36
  article-title: Diarrheagenic Escherichia coli
  publication-title: Braz. J. Microbiol.
  doi: 10.1016/j.bjm.2016.10.015
– volume: 2
  start-page: 747
  year: 2017
  ident: B94
  article-title: The microbiota-gut-brain axis in obesity
  publication-title: Lancet Gastroenterol. Hepatol.
  doi: 10.1016/S2468-1253(17)30147-4
– volume: 272
  start-page: 101
  year: 1996
  ident: B10
  article-title: Age-dependent diarrhea induced by a rotaviral nonstructural glycoprotein
  publication-title: Science
  doi: 10.1126/science.272.5258.101
– volume: 155
  start-page: 377
  year: 1987
  ident: B56
  article-title: Escherichia coli that cause diarrhea: enterotoxigenic, enteropathogenic, enteroinvasive, enterohemorrhagic, and enteroadherent
  publication-title: J. Infect. Dis.
  doi: 10.1093/infdis/155.3.377
– volume: 7
  year: 2016
  ident: B85
  article-title: Bacterial and Fungal Microbiota Changes Distinguish C. difficile Infection from Other Forms of Diarrhea: Results of a Prospective Inpatient Study
  publication-title: Front. Microbiol.
  doi: 10.3389/fmicb.2016.00789
– volume: 321
  start-page: 156
  year: 2019
  ident: B19
  article-title: Effect of Fecal Microbiota Transplantation on 8-Week Remission in Patients With Ulcerative Colitis: A Randomized Clinical Trial
  publication-title: JAMA
  doi: 10.1001/jama.2018.20046
– volume: 7
  year: 2015
  ident: B26
  article-title: Nutritional Keys for Intestinal Barrier Modulation
  publication-title: Front. Immunol.
  doi: 10.3389/fimmu.2015.00612
– volume: 17
  start-page: 909
  year: 2017
  ident: B95
  article-title: Estimates of global, regional, and national morbidity, mortality, and aetiologies of diarrhoeal diseases: a systematic analysis for the Global Burden of Disease Study 2015
  publication-title: Lancet Infect. Dis.
  doi: 10.1016/S1473-3099(17)30276-1
– volume: 8
  year: 2019
  ident: B15
  article-title: Fecal Microbiota Transplantation Controls Murine Chronic Intestinal Inflammation by Modulating Immune Cell Functions and Gut Microbiota Composition
  publication-title: Cells
  doi: 10.3390/cells8060517
– volume: 21
  start-page: 8787
  year: 2015
  ident: B46
  article-title: Role of the normal gut microbiota
  publication-title: World J. Gastroenterol.
  doi: 10.3748/wjg.v21.i29.8787
– volume: 110
  start-page: 278
  year: 2015
  ident: B79
  article-title: Intestinal microbiota and diet in IBS: causes, consequences, or epiphenomena
  publication-title: Am. J. Gastroenterol.
  doi: 10.1038/ajg.2014.427
– volume: 103
  start-page: 6463
  year: 2019
  ident: B65
  article-title: Adhesion mechanisms mediated by probiotics and prebiotics and their potential impact on human health
  publication-title: Appl. Microbiol. Biot.
  doi: 10.1007/s00253-019-09978-7
– volume: 14
  start-page: 491
  year: 2017
  ident: B35
  article-title: Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics
  publication-title: Nat. Rev. Gastroenterol. Hepatol.
  doi: 10.1038/nrgastro.2017.75
– volume: 11
  start-page: 465
  year: 2020
  ident: B72
  article-title: Additional Candida albicans administration enhances the severity of dextran sulfate solution induced colitis mouse model through leaky gut-enhanced systemic inflammation and gut-dysbiosis but attenuated by Lactobacillus rhamnosus L34
  publication-title: Gut Microbes
  doi: 10.1080/19490976.2019.1662712
– volume: 17
  start-page: 322
  year: 2017
  ident: B6
  article-title: Isolation and evaluation of Candida species and their association with CD4+ T cells counts in HIV patients with diarrhoea
  publication-title: Afr. Health Sci.
  doi: 10.4314/ahs.v17i2.5
– volume: 67
  start-page: 2107
  year: 2018
  ident: B40
  article-title: Faecal microbiota transplantation alters gut microbiota in patients with irritable bowel syndrome: results from a randomised, double-blind placebo-controlled study
  publication-title: Gut
  doi: 10.1136/gutjnl-2018-316434
– start-page: 30188
  year: 2020
  ident: B84
  article-title: Development of Microbiome Biobanks - Challenges and Opportunities
  publication-title: Trends Microbiol.
  doi: 10.1016/j.tim.2020.06.009
– volume: 28
  start-page: 901
  year: 2015
  ident: B21
  article-title: Epidemiology, Clinical Presentation, Laboratory Diagnosis, Antimicrobial Resistance, and Antimicrobial Management of Invasive Salmonella Infections
  publication-title: Clin. Microbiol. Rev.
  doi: 10.1128/CMR.00002-15
– volume: 51
  start-page: 201
  year: 2002
  ident: B87
  article-title: Influence of intestinal anaerobes and organic acids on the growth of enterohaemorrhagic Escherichia coli O157:H7
  publication-title: J. Med. Microbiol.
  doi: 10.1099/0022-1317-51-3-201
– volume: 105
  start-page: 1636
  year: 2010
  ident: B33
  article-title: Dose–Response Efficacy of a Proprietary Probiotic Formula of Lactobacillus acidophilus CL1285 and Lactobacillus casei LBC80R for Antibiotic-Associated Diarrhea and Clostridium difficile-Associated Diarrhea Prophylaxis in Adult Patients
  publication-title: Am. J. Gastroenterol.
  doi: 10.1038/ajg.2010.11
– volume: 7
  start-page: 347
  year: 2017
  ident: B41
  article-title: Effects of Debaryomyces hansenii treatment on intestinal microorganisms in mice with antibiotics-induced diarrhea
  publication-title: 3 Biotech.
  doi: 10.1007/s13205-017-0953-9
– volume: 14
  start-page: 2912
  year: 2016
  ident: B98
  article-title: Metagenomic Sequencing with Strain-Level Resolution Implicates Uropathogenic E. coli in Necrotizing Enterocolitis and Mortality in Preterm Infants
  publication-title: Cell Rep.
  doi: 10.1016/j.celrep.2016.03.015
– volume: 21
  start-page: e13062
  year: 2019
  ident: B57
  article-title: Shigella host: Pathogen interactions: Keeping bacteria in the loop
  publication-title: Cell Microbiol
  doi: 10.1111/cmi.13062
– volume: 69
  start-page: 71
  year: 2015
  ident: B69
  article-title: Candida albicans Biofilms and Human Disease
  publication-title: Annu. Rev. Microbiol.
  doi: 10.1146/annurev-micro-091014-104330
– volume: 17
  year: 2021
  ident: B88
  article-title: Gut microbiome, prebiotics, intestinal permeability and diabetes complications
  publication-title: Best Pract. Res. Cl. En.
  doi: 10.1016/j.beem.2021.101507
– volume: 26
  start-page: e920879
  year: 2020
  ident: B100
  article-title: Bacterial Lactase Gene Characteristics in Intestinal Contents of Antibiotic-Associated Diarrhea Mice Treated with Debaryomyces hansenii
  publication-title: Med. Sci. Monitor.
  doi: 10.12659/MSM.920879
– volume: 6
  start-page: 379
  year: 2020
  ident: B7
  article-title: Opportunities of prebiotics for the intestinal health of monogastric animals
  publication-title: Anim. Nutr
  doi: 10.1016/j.aninu.2020.08.001
– volume: 19
  start-page: 55
  year: 2020
  ident: B30
  article-title: Gut microbiota in human metabolic health and disease
  publication-title: Nat. Rev. Microbiol.
  doi: 10.1038/s41579-020-0433-9
– volume: 117
  start-page: 209
  year: 2017
  ident: B82
  article-title: A fermented milk concentrate and a combination of short-chain galacto-oligosaccharides/long-chain fructo-oligosaccharides/pectin-derived acidic oligosaccharides protect suckling rats from rotavirus gastroenteritis
  publication-title: Br. J. Nutr.
  doi: 10.1017/S0007114516004566
– volume: 9
  year: 2018
  ident: B83
  article-title: Preventive Effect of a Synbiotic Combination of Galacto- and Fructooligosaccharides Mixture With Bifidobacterium breve M-16V in a Model of Multiple Rotavirus Infections
  publication-title: Front. Immunol.
  doi: 10.3389/fimmu.2018.01318
– volume: 12
  year: 2020
  ident: B8
  article-title: Strain-Specific Probiotic Properties of Bifidobacteria and Lactobacilli for the Prevention of Diarrhea Caused by Rotavirus in a Preclinical Model
  publication-title: Nutrients
  doi: 10.3390/nu12020498
– volume: 535
  start-page: 56
  year: 2016
  ident: B89
  article-title: Diet-microbiota interactions as moderators of human metabolism
  publication-title: Nature
  doi: 10.1038/nature18846
– volume: 10
  start-page: 12636
  year: 2020
  ident: B73
  article-title: Protective action of Bacillus clausii probiotic strains in an in vitro model of Rotavirus infection
  publication-title: Sci. Rep.-UK
  doi: 10.1038/s41598-020-69533-7
– volume: 50
  year: 2020
  ident: B18
  article-title: Chronic diarrhea
  publication-title: Curr. Prob. Pediatr. Ad.
  doi: 10.1016/j.cppeds.2020.100841
– volume: 245
  start-page: 56
  year: 2012
  ident: B50
  article-title: The streptomycin mouse model for Salmonella diarrhea: functional analysis of the microbiota, the pathogen’s virulence factors, and the host’s mucosal immune response
  publication-title: Immunol. Rev.
  doi: 10.1111/j.1600-065X.2011.01070.x
– volume: 30
  start-page: 779
  year: 2001
  ident: B37
  article-title: Viral causes of diarrhea
  publication-title: Gastroenterol. Clin. N.
  doi: 10.1016/s0889-8553(05)70210-7
– volume: 336
  start-page: 1325
  year: 2012
  ident: B51
  article-title: Regulated virulence controls the ability of a pathogen to compete with the gut microbiota
  publication-title: Science
  doi: 10.1126/science.1222195
– volume: 9
  start-page: 4122
  year: 2019
  ident: B38
  article-title: Vibrio cholerae autoinducer-1 enhances the virulence of enteropathogenic Escherichia coli
  publication-title: Sci. Rep.
  doi: 10.1038/s41598-019-40859-1
– volume: 152
  start-page: 799
  year: 2017
  ident: B71
  article-title: Efficacy of Sterile Fecal Filtrate Transfer for Treating Patients With Clostridium difficile Infection
  publication-title: Gastroenterology
  doi: 10.1053/j.gastro.2016.11.010
– volume: 99
  start-page: 255
  year: 2021
  ident: B77
  article-title: Impact of prebiotics on immune response: from the bench to the clinic
  publication-title: Immunol. Cell Biol.
  doi: 10.1111/imcb.12409
– volume: 35
  start-page: 992
  year: 2016
  ident: B54
  article-title: A Systematic Review of the Effect of Rotavirus Vaccination on Diarrhea Outcomes Among Children Younger Than 5 Years
  publication-title: Pediatr. Infect. Dis. J.
  doi: 10.1097/INF.0000000000001232
– volume: 3
  start-page: 17
  year: 2018
  ident: B48
  article-title: Faecal microbiota transplantation versus placebo for moderate-to-severe irritable bowel syndrome: a double-blind, randomised, placebo-controlled, parallel-group, single-centre trial
  publication-title: Lancet Gastroenterol. Hepatol.
  doi: 10.1016/S2468-1253(17)30338-2
– volume: 152
  start-page: 515
  year: 2017
  ident: B16
  article-title: Pathophysiology, Evaluation, and Management of Chronic Watery Diarrhea
  publication-title: Gastroenterology
  doi: 10.1053/j.gastro.2016.10.014
– volume: 65
  start-page: 1
  year: 2020
  ident: B68
  article-title: Shigella flexneri: an emerging pathogen
  publication-title: Folia Microbiol.
  doi: 10.1007/s12223-020-00773-w
– volume: 38
  start-page: 1211
  year: 2019
  ident: B22
  article-title: Clostridium difficile infection: review
  publication-title: Eur. J. Clin. Microbiol.
  doi: 10.1007/s10096-019-03539-6
– volume: 135
  start-page: 145
  year: 1996
  ident: B76
  article-title: Role of Candida in indirect pathogenesis of antibiotic associated diarrhoea in infants
  publication-title: Mycopathologia
  doi: 10.1007/BF00632335
– volume: 33
  start-page: S17
  year: 2001
  ident: B91
  article-title: Probiotics in the treatment and prevention of acute infectious diarrhea in infants and children: a systematic review of published randomized, double-blind, placebo-controlled trials
  publication-title: J. Pediatr. Gastr. Nutr.
  doi: 10.1097/00005176-200110002-00004
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Snippet Diarrhea is a common problem to the whole world and the occurrence of diarrhea is highly associated with gut microbiota, such as bacteria, fungi, and viruses....
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SubjectTerms Cellular and Infection Microbiology
diarrhea
fecal microbiota transplantation
gut microbiota
intestinal health
probiotics
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Title Gut Microbiota and Diarrhea: An Updated Review
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