Gut Microbiota and Diarrhea: An Updated Review

Diarrhea is a common problem to the whole world and the occurrence of diarrhea is highly associated with gut microbiota, such as bacteria, fungi, and viruses. Generally, diarrheal patients or animals are characterized by gut microbiota dysbiosis and pathogen infections may lead to diarrheal phenotyp...

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Published inFrontiers in cellular and infection microbiology Vol. 11; p. 625210
Main Authors Li, Yunxia, Xia, Siting, Jiang, Xiaohan, Feng, Can, Gong, Saiming, Ma, Jie, Fang, Zhengfeng, Yin, Jie, Yin, Yulong
Format Journal Article
LanguageEnglish
Published Switzerland Frontiers Media S.A 15.04.2021
Subjects
Cellular and Infection Microbiology
diarrhea
fecal microbiota transplantation
gut microbiota
intestinal health
probiotics
intestinal health
diarrhea
fecal microbiota transplantation
gut microbiota
probiotics
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Summary:Diarrhea is a common problem to the whole world and the occurrence of diarrhea is highly associated with gut microbiota, such as bacteria, fungi, and viruses. Generally, diarrheal patients or animals are characterized by gut microbiota dysbiosis and pathogen infections may lead to diarrheal phenotypes. Of relevance, reprograming gut microbiota communities by dietary probiotics or fecal bacteria transplantation are widely introduced to treat or prevent diarrhea. In this review, we discussed the influence of the gut microbiota in the infection of diarrhea pathogens, and updated the research of reshaping the gut microbiota to prevent or treat diarrhea for the past few years. Together, gut microbiota manipulation is of great significance to the prevention and treatment of diarrhea, and further insight into the function of the gut microbiota will help to discover more anti-diarrhea probiotics.
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Reviewed by: Thibault Géry Sana, Le nouvel Institut national de recherche sur l'agriculture, l’alimentation et l’environnement en France INRAE, France; Yuehe Ding, University of Massachusetts Medical School, United States
This article was submitted to Microbiome in Health and Disease, a section of the journal Frontiers in Cellular and Infection Microbiology
Edited by: Qiyuan Yang, University of Massachusetts Medical School, United States
ISSN:2235-2988
2235-2988
DOI:10.3389/fcimb.2021.625210